Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6290953 | 0.98 | CHRNB2 (0.48) | CHRNB2CHRNA4 | |
| SCHEMBL6138308 | 0.83 | CHRNB1 (0.40) | CHRNB2CHRNA4 | |
| SCHEMBL20255433 | 0.81 | LRRK2 (0.34) | — | |
| Hydrochloric Acid SCHEMBL6138601 | 0.81 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL20249228 | 0.79 | LRRK2 (0.33) | — | |
| SCHEMBL5432128 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNA4 | |
| SCHEMBL4646918 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNA4 | |
| SCHEMBL4642542 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL5109777 | 0.78 | CHRNB2 (0.52) | CHRNB2CHRNA4 | |
| SCHEMBL30703558 | 0.76 | CHRNB2 (0.47) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170281-B1 | 1,1- and 1,2-disubstituted cyclopropanes, process for their preparation and pharmaceutical compositions thereof | SERVIER LAB (FR) | 2005-12-21 | — | — | EP | claimed |
| EP-1170281-A1 | 1,1- and 1,2-disubstituted cyclopropanes, process for their preparation and pharmaceutical compositions thereof | LES LABORATOIRES SERVIER (FR) | 2002-01-09 | — | — | EP | claimed |
| EP-1170281-B1 | 1,1- and 1,2-disubstituted cyclopropanes, process for their preparation and pharmaceutical compositions thereof | SERVIER LAB (FR) | 2005-12-21 | — | — | EP | disclosed |
| EP-1170281-A1 | 1,1- and 1,2-disubstituted cyclopropanes, process for their preparation and pharmaceutical compositions thereof | LES LABORATOIRES SERVIER (FR) | 2002-01-09 | — | — | EP | disclosed |