SCHEMBL6138088

SCHEMBL6138088

O=C(CC1CCCCC1)NC(CO)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.49
EPHX1 P07099 1/20 0.49
KMT2A Q03164 1/20 0.49
EPHX2 P34913 3/20 0.45
GRN P28799 1/20 0.43
SORT1 Q99523 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
TGFBR1 P36897 3/20 0.42
MME P08473 1/20 0.41
ERCC1 P07992 1/20 0.39
ERCC4 Q92889 1/20 0.39
AAK1 Q2M2I8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6138089 1.00 HPGD (0.49) HPGDEPHX1KMT2AEPHX2GRN
SCHEMBL10660233 0.83 HPGD (0.51) HPGDKMT2AEPHX2GRNSORT1
SCHEMBL4057394 0.82 EPHX1 (0.45) HPGDEPHX1KMT2AEPHX2GRN
SCHEMBL4313036 0.82 ALDH1A1 (0.51) HPGDEPHX1KMT2AEPHX2GRN
SCHEMBL4313039 0.82 ALDH1A1 (0.51) HPGDEPHX1KMT2AEPHX2GRN
SCHEMBL5274437 0.82 KMT2A (0.45) HPGDEPHX1KMT2AEPHX2GRN
SCHEMBL5274432 0.82 KMT2A (0.45) HPGDEPHX1KMT2AEPHX2GRN
SCHEMBL4058648 0.80 SMN1; SMN2 (0.42) HPGDEPHX1KMT2AEPHX2GRN
SCHEMBL8895660 0.80 ALDH1A1 (0.53) HPGDEPHX1KMT2AGRNSORT1
SCHEMBL5275396 0.80 EPHX2 (0.44) HPGDEPHX1KMT2AEPHX2GRN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1047391-A4 ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS GILLETTE CO (US) 2005-01-19 EP claimed
US-6238655-B1 USEFUL IN THE FORMULATION OF DEODORANTS, ANTIPERSPIRANTS, BODY SPRAYS, AND OTHER SKIN TREATMENT COMPOSITIONS. THE GILLETTE COMPANY 2001-05-29 US claimed
EP-1047391-A1 ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS THE GILLETTE COMPANY (US) 2000-11-02 EP claimed
WO-1999030679-A1 α-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS THE GILLETTE COMPANY (US) 1999-06-24 WO claimed
EP-1047391-A4 ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS GILLETTE CO (US) 2005-01-19 EP disclosed
US-6238655-B1 USEFUL IN THE FORMULATION OF DEODORANTS, ANTIPERSPIRANTS, BODY SPRAYS, AND OTHER SKIN TREATMENT COMPOSITIONS. THE GILLETTE COMPANY 2001-05-29 US disclosed
EP-1047391-A1 ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS THE GILLETTE COMPANY (US) 2000-11-02 EP disclosed
WO-1999030679-A1 α-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS THE GILLETTE COMPANY (US) 1999-06-24 WO disclosed