Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670644 | 0.85 | PTGS2 (0.51) | PTGS2CYP19A1TLR9PTGS1ABCB1 | |
| SCHEMBL6137889 | 0.85 | PTGS2 (0.51) | PTGS2CYP19A1TLR9PTGS1 | |
| SCHEMBL3670074 | 0.80 | TLR9 (0.50) | PTGS2CYP19A1TLR9PTGS1MAPT | |
| SCHEMBL6431521 | 0.76 | PTGS2 (0.51) | PTGS2CYP19A1ALOX5TLR9PTGS1 | |
| SCHEMBL6431529 | 0.76 | PTGS2 (0.51) | PTGS2CYP19A1ALOX5TLR9PTGS1 | |
| SCHEMBL4260783 | 0.75 | MAPT (0.51) | PTGS2CYP19A1ALOX5TLR9PTGS1 | |
| SCHEMBL4260782 | 0.75 | MAPT (0.51) | PTGS2CYP19A1ALOX5TLR9PTGS1 | |
| SCHEMBL4255525 | 0.70 | MAPT (0.53) | PTGS2CYP19A1ALOX5TLR9PTGS1 | |
| SCHEMBL3671688 | 0.70 | ALOX5 (0.62) | PTGS2CYP19A1ALOX5TLR9PTGS1 | |
| SCHEMBL4255529 | 0.70 | MAPT (0.53) | PTGS2CYP19A1ALOX5TLR9PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435894-A4 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | GALILEO PHARMACEUTICALS INC (US) | 2005-07-06 | — | — | EP | disclosed |
| EP-1435894-A2 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | Galileo Pharmaceuticals, Inc. (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003009807-A2 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | GALILEO LABORATORIES, INC. (US) | 2003-02-06 | — | — | WO | disclosed |