SCHEMBL6138228

SCHEMBL6138228

CC1(C)CC1(N)CCOc1cccnc1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 6/20 0.53
CHRNA4 P43681 6/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6138358 0.85 CHRNB2 (0.47) CHRNB2CHRNA4
SCHEMBL6253152 0.77 CHRNB2 (0.53) CHRNB2CHRNA4
SCHEMBL1622662 0.76 CHRNB2 (0.62) CHRNB2CHRNA4
SCHEMBL31483083 0.76 CHRNB2 (0.62) CHRNB2CHRNA4
SCHEMBL6137939 0.75 CHRNB2 (0.60) CHRNB2CHRNA4
SCHEMBL4805267 0.74 CHRNB2 (0.61) CHRNB2CHRNA4
SCHEMBL6138243 0.73 CHRNB2 (0.59) CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL6291503 0.73 CHRNB2 (0.59) CHRNB2CHRNA4
SCHEMBL6254874 0.73 CHRNB2 (0.59) CHRNB2CHRNA4
SCHEMBL30601967 0.72 CHRNB2 (0.51) CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1170281-B1 1,1- and 1,2-disubstituted cyclopropanes, process for their preparation and pharmaceutical compositions thereof SERVIER LAB (FR) 2005-12-21 EP disclosed