SCHEMBL6138474

SCHEMBL6138474

Nc1cc(N)cc(Oc2ccc(Oc3cc(N)cc(N)c3)cc2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
NPC1 O15118 2/20 0.64
RAB9A P51151 2/20 0.64
NLRP3 Q96P20 1/20 0.64
ALDH1A1 P00352 6/20 0.63
TDP1 Q9NUW8 2/20 0.63
CYP3A4 P08684 1/20 0.63
TSHR P16473 1/20 0.63
ST14 Q9Y5Y6 3/20 0.59
F2 P00734 1/20 0.59
PRSS1 P07477 1/20 0.59
PRSS2 P07478 1/20 0.59
PRSS3 P35030 1/20 0.59
SMN1; SMN2 Q16637 3/20 0.58
MAPT P10636 5/20 0.54
MITF O75030 1/20 0.54
GAA P10253 1/20 0.54
GFER P55789 1/20 0.54
NLRP1 Q9C000 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20347020 0.95 ALDH1A1 (0.74) MEN1KMT2ANPC1RAB9ANLRP3
SCHEMBL3653673 0.95 ALDH1A1 (0.74) MEN1KMT2ANPC1RAB9ANLRP3
SCHEMBL6138483 0.91 MEN1 (0.52) MEN1KMT2ANPC1RAB9ANLRP3
SCHEMBL23759 0.89 MEN1 (0.79) MEN1KMT2ANPC1RAB9ANLRP3
SCHEMBL3937575 0.88 MEN1 (0.64) MEN1KMT2ANPC1RAB9ANLRP3
SCHEMBL7804603 0.87 MEN1 (0.76) MEN1KMT2ANPC1RAB9ANLRP3
SCHEMBL8999880 0.83 MEN1 (0.53) MEN1KMT2ANPC1RAB9ANLRP3
SCHEMBL21186230 0.83 MEN1 (0.59) MEN1KMT2ANPC1RAB9ANLRP3
SCHEMBL7716208 0.83 MEN1 (0.48) MEN1KMT2ANPC1RAB9ANLRP3
SCHEMBL12774829 0.82 MEN1 (0.48) MEN1KMT2ANPC1RAB9ANLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11377521-B2 Linear and branched polyimide composition SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-07-05 US disclosed
US-11286347-B2 Compositions and articles made from branched polyetherimides SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-03-29 US disclosed
WO-2021138401-A1 REINFORCED LINEAR AND BRANCHED POLYIMIDE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-07-08 WO disclosed
US-20200207913-A1 PHOSPHONIUM BROMIDE TERMINATED POLYIMIDE WITH HIGH TENSILE PROPERTIES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-07-02 US disclosed
US-20200115501-A1 BRANCHED POLYIMIDE COMPOSITIONS, METHOD OF MANUFACTURE, AND USES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-04-16 US disclosed
US-20190315963-A1 LINEAR AND BRANCHED POLYIMIDE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-10-17 US disclosed
US-20190211153-A1 POLYIMIDE AND POLYETHERIMIDE FROM METAL CONTAINING OLIGOMERS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-07-11 US disclosed
WO-2018126162-A1 COMPOSITIONS AND ARTICLES MADE FROM BRANCHED POLYETHERIMIDES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-07-05 WO disclosed
WO-2018126154-A1 LINEAR AND BRANCHED POLYIMIDE COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-07-05 WO disclosed
WO-2018126141-A1 BRANCHED POLYIMIDE COMPOSITIONS, METHOD OF MANUFACTURE, AND USES THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-07-05 WO disclosed
EP-1117102-B1 Method of manufacturing material for forming insulating film JSR CORP (JP) 2005-08-10 EP disclosed
US-6642352-B2 Providing a silicon inorganic polymer compound or polyarylenes or polyphenylene ether organic polymer compound, treating the polymeric compound with a zeta-potential producing filter material, and producing curable polymer compound JSR CORPORATION (JP) 2003-11-04 US disclosed
US-20010009936-A1 Method of manufacturing material for forming insulating film JSR CORPORATION (JP) 2001-07-26 US disclosed
EP-1117102-A2 Method of manufacturing material for forming insulating film JSR Corporation (JP) 2001-07-18 EP disclosed