Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138851 | 1.00 | HDAC1 (0.50) | HDAC1HDAC8HDAC2HRH3HDAC6 | |
| SCHEMBL6138517 | 1.00 | HDAC1 (0.50) | HDAC1HDAC8HDAC2HRH3HDAC6 | |
| Hydrochloric Acid SCHEMBL6138931 | 0.99 | HDAC1 (0.49) | HDAC1HDAC8HDAC2HRH3HDAC6 | |
| Hydrochloric Acid SCHEMBL6138939 | 0.99 | HDAC1 (0.49) | HDAC1HDAC8HDAC2HRH3HDAC6 | |
| Hydrochloric Acid SCHEMBL6138946 | 0.99 | HDAC1 (0.49) | HDAC1HDAC8HDAC2HRH3HDAC6 | |
| SCHEMBL6138934 | 0.88 | HDAC2 (0.51) | HDAC1HDAC8HDAC2HRH3HDAC6 | |
| SCHEMBL6139137 | 0.88 | HDAC2 (0.51) | HDAC1HDAC8HDAC2HRH3HDAC6 | |
| Hydrochloric Acid SCHEMBL6138884 | 0.86 | HDAC2 (0.50) | HDAC1HDAC8HDAC2HRH3HDAC6 | |
| Hydrochloric Acid SCHEMBL6138888 | 0.86 | HDAC2 (0.50) | HDAC1HDAC8HDAC2HRH3HDAC6 | |
| SCHEMBL6138877 | 0.85 | HRH3 (0.49) | HDAC1HDAC8HDAC2HRH3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1215203-B1 | HYDROXAMIC ACID DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2005-02-16 | — | — | EP | claimed |
| US-20040214896-A1 | Hydroxamic acid derivatives, the methods for preparation thereof and pharmaceutical compositions comprising thereof, as an active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2004-10-28 | — | — | US | claimed |
| EP-1215203-A1 | HYDROXAMIC ACID DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-06-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214896-A1 | Hydroxamic acid derivatives, the methods for preparation thereof and pharmaceutical compositions comprising thereof, as an active ingredient | HIF1AN, IL6, PYGM | HDAC1 942/4885HDAC8 1134/4885HDAC2 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.