Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 3/20 | 0.46 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.46 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.30 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521796 | 0.81 | SLC6A12 (0.65) | SLC6A12SLC6A11SLC6A13HSD11B1ALOX5 | |
| SCHEMBL7813782 | 0.81 | SLC6A12 (0.65) | SLC6A12SLC6A11SLC6A13HSD11B1ALOX5 | |
| SCHEMBL28961634 | 0.81 | SLC6A12 (0.65) | SLC6A12SLC6A11SLC6A13HSD11B1ALOX5 | |
| SCHEMBL6267915 | 0.75 | — | — | |
| SCHEMBL6264783 | 0.75 | — | — | |
| SCHEMBL6073028 | 0.75 | — | — | |
| SCHEMBL6265845 | 0.75 | — | — | |
| SCHEMBL7454104 | 0.75 | — | — | |
| SCHEMBL10248670 | 0.74 | SLC6A12 (0.37) | SLC6A12SLC6A11SLC6A13HSD11B1 | |
| SCHEMBL15559758 | 0.72 | SLC6A12 (0.41) | SLC6A12SLC6A11SLC6A13HSD11B1KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170281-B1 | 1,1- and 1,2-disubstituted cyclopropanes, process for their preparation and pharmaceutical compositions thereof | SERVIER LAB (FR) | 2005-12-21 | — | — | EP | claimed |