Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 6/20 | 0.46 |
| ▸ | CASP5 | P51878 | 6/20 | 0.46 |
| ▸ | CASP4 | P49662 | 5/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6774817 | 0.99 | KDM4E (0.46) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6139052 | 0.97 | KDM4E (0.49) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6772881 | 0.96 | KDM4E (0.48) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6778734 | 0.89 | ALDH1A1 (0.44) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6774850 | 0.86 | ALDH1A1 (0.45) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6771210 | 0.85 | MEN1 (0.57) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6772490 | 0.83 | MEN1 (0.59) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6778263 | 0.81 | LMNA (0.55) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6774183 | 0.80 | MEN1 (0.62) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6138665 | 0.80 | KDM4E (0.68) | KDM4EALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1277746-B1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions thereof | SERVIER LAB (FR) | 2005-05-11 | — | — | EP | disclosed |
| EP-1277746-A2 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions thereof | Les Laboratoires Servier (FR) | 2003-01-22 | — | — | EP | disclosed |