Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497231 | 0.89 | — | — | |
| SCHEMBL10071490 | 0.89 | ALDH1A1 (0.39) | TSHRALDH1A1CYP3A4CA12CA1 | |
| SCHEMBL1155676 | 0.89 | — | — | |
| SCHEMBL8978821 | 0.87 | TSHR (0.63) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL11798288 | 0.87 | TSHR (0.63) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL10071496 | 0.87 | ALDH1A1 (0.43) | TSHRALDH1A1CYP3A4CA12CA1 | |
| SCHEMBL18807559 | 0.87 | — | — | |
| SCHEMBL5703187 | 0.87 | TSHR (0.42) | TSHRALDH1A1CYP3A4NAAATDP1 | |
| SCHEMBL9498948 | 0.87 | TSHR (0.63) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL11810777 | 0.87 | TSHR (0.63) | TSHRALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017189953-A1 | POLY(KETALS) AND RELATED COMPOSITIONS AND METHODS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2017-11-02 | — | — | WO | disclosed |
| EP-1240139-B1 | METHOD FOR PRODUCING N-ALKENYL AMIDES | BASF AG (DE) | 2005-11-09 | — | — | EP | disclosed |
| US-6624303-B2 | By reacting the corresponding NH-amides with acetylenes in the liquid phase using a basic alkali metal compound as catalyst and as cocatalyst (di- or tri-)1,4-butanediol mono- and diethers; N-vinyl-2-pyrrolidone from pyrrolidone | BASF AKTIENGESELLSCHAFT (DE) | 2003-09-23 | — | — | US | disclosed |
| EP-1268380-B1 | METHOD FOR PRODUCING ALKENYL ETHERS | BASF AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-20030114715-A1 | Method for producing alkenyl ethers | BOETTCHER ARND (DE) | 2003-06-19 | — | — | US | disclosed |
| US-20030028035-A1 | Method for producing n-alkenyl amides | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028035-A1 | Method for producing n-alkenyl amides | NAT1, H1-2, H1-0 | TSHR 2175/4885ALDH1A1 472/4885CYP3A4 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.