Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567730 | 0.88 | GAA (0.78) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5081739 | 0.83 | GAA (0.62) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5569071 | 0.82 | GAA (0.69) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL17428468 | 0.82 | HSD11B1 (0.51) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5080904 | 0.77 | GAA (0.55) | GAAALDH1A1MEN1KMT2A | |
| SCHEMBL5081738 | 0.77 | GAA (0.55) | GAAALDH1A1MEN1KMT2A | |
| SCHEMBL17702628 | 0.76 | GAA (0.42) | GAAALDH1A1LMNADPP4HSD11B1 | |
| SCHEMBL2849063 | 0.76 | MEN1 (0.50) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3325046 | 0.75 | HSD11B1 (0.73) | MEN1KMT2AHSD11B1CYP3A4 | |
| SCHEMBL5081795 | 0.75 | GAA (0.52) | GAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505053-A1 | Adamantanetricarboxylic acid derivatives | Daicel Chemical Industries, Ltd. (JP) | 2005-02-09 | — | — | EP | disclosed |