Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936515 | 0.85 | KMT2A (0.54) | CYP3A4NFKB1PMP22KMT2AALDH1A1 | |
| SCHEMBL6140556 | 0.81 | KMT2A (0.68) | CYP3A4NFKB1PMP22KMT2AALDH1A1 | |
| SCHEMBL6140550 | 0.78 | TP53 (0.68) | KMT2AALDH1A1POLBMAPTGAA | |
| SCHEMBL5653277 | 0.78 | KMT2A (0.50) | CYP3A4NFKB1PMP22KMT2AALDH1A1 | |
| SCHEMBL30168172 | 0.77 | ALDH1A1 (0.57) | CYP3A4NFKB1PMP22KMT2AALDH1A1 | |
| SCHEMBL78187 | 0.77 | ALDH1A1 (0.57) | CYP3A4NFKB1PMP22KMT2AALDH1A1 | |
| SCHEMBL12543336 | 0.77 | CYP3A4 (0.51) | CYP3A4NFKB1PMP22KMT2AALDH1A1 | |
| SCHEMBL22816934 | 0.76 | ALDH1A1 (0.60) | CYP3A4NFKB1PMP22KMT2AALDH1A1 | |
| SCHEMBL31680519 | 0.75 | CYP3A4 (1.00) | CYP3A4NFKB1PMP22KMT2AALDH1A1 | |
| SCHEMBL1322530 | 0.75 | CYP3A4 (1.00) | CYP3A4NFKB1PMP22KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182260-A1 | Process for the preparation of cyclic imides in the presence of polyphosphoric acid | MERCK PATENT GMBH (DE) | 2005-08-18 | — | — | US | disclosed |
| EP-1506173-A1 | METHOD FOR PRODUCING CYCLIC IMIDES IN THE PRESENCE OF POLYPHOSPHORIC ACID | MERCK PATENT GmbH (DE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097600-A1 | METHOD FOR PRODUCING CYCLIC IMIDES IN THE PRESENCE OF POLYPHOSPHORIC ACID | MERCK PATENT GMBH (DE) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182260-A1 | Process for the preparation of cyclic imides in the presence of polyphosphoric acid | PPIP5K2, ITPA, IPMK | CYP3A4 436/4885NFKB1 1399/4885PMP22 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.