SCHEMBL6140465

SCHEMBL6140465

CC(C)(C)Oc1cccc([S+](c2cccc(OCc3ccccn3)c2)c2cccc(OCc3ccccn3)c2)c1.CC(C)(C)c1ccc(S(=O)(=O)[O-])cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
POLB P06746 1/20 0.40
TLR4 O00206 1/20 0.39
TLR2 O60603 1/20 0.39
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ALOX5AP P20292 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140428 0.89 TLR4 (0.39) ALDH1A1HTTLMNASMN1; SMN2MEN1
SCHEMBL6140607 0.87 ALDH1A1 (0.47) ALDH1A1NPC1RAB9AHTTLMNA
SCHEMBL6140822 0.87 SMN1; SMN2 (0.39) ALDH1A1HTTLMNASMN1; SMN2TLR4
SCHEMBL6140741 0.87 SMN1; SMN2 (0.39) ALDH1A1HTTLMNASMN1; SMN2TLR4
SCHEMBL6140145 0.84 POLB (0.41) ALDH1A1NPC1RAB9AHTTLMNA
SCHEMBL6140456 0.84 TLR4 (0.47) ALDH1A1SMN1; SMN2MEN1KMT2ATLR4
SCHEMBL6140220 0.84 ALDH1A1 (0.52) ALDH1A1NPC1RAB9AHTTLMNA
SCHEMBL6140596 0.84 TLR4 (0.45) ALDH1A1HTTLMNASMN1; SMN2TLR4
SCHEMBL6140242 0.82 TLR4 (0.43) ALDH1A1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL6140321 0.80 SYK (0.36) ALDH1A1HTTLMNASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6955939-B1 Memory element formation with photosensitive polymer dielectric ADVANCED MICRO DEVICES, INC. (US) 2005-10-18 US disclosed
US-6878961-B2 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. (US) 2005-04-12 US disclosed
US-20050045877-A1 PHOTOSENSITIVE POLYMERIC MEMORY ELEMENTS MORGAN STANLEY SENIOR FUNDING, INC. 2005-03-03 US disclosed
US-6825060-B1 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. 2004-11-30 US disclosed
US-6534243-B1 A coating containing a cleaving compound to trim resist features; permitting a deprotection region to form within an inner portion of the patterned resist; removing coating and deprotection region to provide a second patterned feature ADVANCED MICRO DEVICES, INC. 2003-03-18 US disclosed
US-6492075-B1 COATING WITH CLEAVING COMPOUND TO CONTROLLABLY DECREASE SIZE OF DEVELOPED RESIST ADVANCED MICRO DEVICES, INC. 2002-12-10 US disclosed
US-6274289-B1 Chemical resist thickness reduction process ADVANCED MICRO DEVICES, INC. 2001-08-14 US disclosed
US-5847218-A Sulfonium salts and chemically amplified positive resist compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-08 US disclosed