Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 1/20 | 0.72 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.60 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140448 | 0.87 | SMN1; SMN2 (0.57) | CA12CA9GPR27AVPR2HTT | |
| SCHEMBL8752463 | 0.84 | CA12 (1.00) | CA12CA9HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL10947961 | 0.81 | CA12 (0.76) | CA12CA9HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3046360 | 0.79 | CA12 (0.78) | CA12CA9HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6809700 | 0.78 | CA12 (0.76) | CA12CA9HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL10740742 | 0.77 | GAA (0.54) | CA12CA9ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12505411 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KDM4EHSD17B10LMNA | |
| SCHEMBL633327 | 0.77 | CA12 (0.83) | CA12CA9HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6792745 | 0.77 | CA12 (0.74) | CA12CA9HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6108804 | 0.77 | MCHR1 (0.60) | CA12CA9GPR27AVPR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497260-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM Pharma A/S (DK) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087045-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |