SCHEMBL6140905

SCHEMBL6140905

CCCCOC1([C]=O)CC1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TSHR P16473 2/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
ATM Q13315 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6141152 0.94 CA1 (0.33) TSHRCA1CA2
SCHEMBL6141013 0.92 TSHR (0.37) TSHRCA1CA2
SCHEMBL6141462 0.86
SCHEMBL6141433 0.72 ALDH1A1 (0.35) ALDH1A1
SCHEMBL3180047 0.69 ADRB2 (0.39) CYP3A4ALDH1A1TSHRADRB2ADRB1
SCHEMBL6141273 0.67 ALDH1A1 (0.31) ALDH1A1
SCHEMBL6160914 0.65 ADRB2 (0.36) CYP3A4ALDH1A1TSHRADRB2ADRB1
SCHEMBL9397695 0.64 ADRB2 (0.39) CYP3A4ALDH1A1TSHRADRB2ADRB1
SCHEMBL14778086 0.64 MEN1 (0.35) CYP3A4ALDH1A1TSHRADRB2ADRB1
SCHEMBL6161200 0.64 MEN1 (0.35) CYP3A4ALDH1A1TSHRADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1517881-A1 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES Syngenta Participations AG (CH) 2005-03-30 EP disclosed
WO-2004002943-A1 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2004-01-08 WO disclosed