Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37463 | 0.86 | IDO1 (0.70) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL6141174 | 0.85 | IDO1 (0.63) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL6140986 | 0.84 | TSHR (0.59) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL6141311 | 0.84 | IDO1 (0.58) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL6198529 | 0.84 | IDO1 (0.58) | IDO1AKR1C3LOXL2TSHRRAB9A | |
| SCHEMBL8924433 | 0.84 | IDO1 (0.58) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL8424297 | 0.84 | IDO1 (0.58) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL12478072 | 0.82 | IDO1 (0.56) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL629644 | 0.81 | IDO1 (0.63) | IDO1AKR1C3LOXL2TSHRCA12 | |
| SCHEMBL15137511 | 0.81 | IDO1 (0.54) | IDO1AKR1C3LOXL2TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517881-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES | Syngenta Participations AG (CH) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004002943-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-08 | — | — | WO | disclosed |