Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | RNF4 | P78317 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140972 | 0.93 | PARP1 (0.46) | PARP1RNF4MCHR1PARP15PARP10 | |
| SCHEMBL6140723 | 0.91 | GAA (0.50) | PARP1PARP15PARP10TSHRACHE | |
| SCHEMBL6141139 | 0.83 | L3MBTL1 (0.46) | PARP1PARP15PARP10ACHE | |
| SCHEMBL6108768 | 0.80 | MCHR1 (0.73) | MCHR1 | |
| SCHEMBL6140461 | 0.79 | PARP15 (0.62) | PARP15PARP10CTNNB1 | |
| SCHEMBL6141239 | 0.79 | PARP15 (0.65) | PARP1PARP15PARP10CTNNB1 | |
| SCHEMBL6141253 | 0.76 | PARP15 (0.46) | PARP15PARP10CTNNB1PLA2G10 | |
| SCHEMBL6141248 | 0.76 | FFAR1 (0.56) | — | |
| SCHEMBL6141272 | 0.76 | HIF1A (0.56) | MCHR1PARP15PARP10 | |
| SCHEMBL6108706 | 0.74 | MCHR1 (0.70) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497260-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM Pharma A/S (DK) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087045-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |