Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.46 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141007 | 0.91 | PARP1 (0.48) | ACHEPARP15PARP1TSHRPARP10 | |
| SCHEMBL6141139 | 0.87 | L3MBTL1 (0.46) | GAAHPGDBCHEACHEPARP15 | |
| SCHEMBL6140972 | 0.83 | PARP1 (0.46) | PARP15MEN1KMT2APARP1PARP10 | |
| SCHEMBL12970697 | 0.78 | LMNA (0.57) | GAAHPGDPARP15MEN1KMT2A | |
| SCHEMBL6111720 | 0.77 | MCHR1 (0.64) | ACHE | |
| SCHEMBL10949296 | 0.77 | SLC16A3 (0.57) | GAAHPGDSLC16A3SLC16A1MEN1 | |
| SCHEMBL13177255 | 0.76 | KDM4E (0.47) | GAAMEN1KMT2ATSHRKDM4E | |
| SCHEMBL11596722 | 0.76 | ACHE (0.54) | GAAHPGDBCHEACHEPARP15 | |
| SCHEMBL6141196 | 0.75 | MAPT (0.53) | GAAHPGDMEN1KMT2AKDM4E | |
| SCHEMBL6155453 | 0.75 | ACHE (0.50) | GAAHPGDBCHEACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497260-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM Pharma A/S (DK) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087045-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |