Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Etidronic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.93 |
| ▸ | FDPS | P14324 | 15/20 | 0.47 |
| ▸ | PGK1 | P00558 | 1/20 | 0.45 |
| ▸ | PGK2 | P07205 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etidronic Acid SCHEMBL10957057 | 0.97 | LMNA (0.87) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL18607 | 0.96 | LMNA (1.00) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL10532992 | 0.96 | LMNA (1.00) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL1924063 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL10524952 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL17580248 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL10706705 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL3896726 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL3130855 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 | |
| Etidronic Acid SCHEMBL205727 | 0.93 | LMNA (0.93) | LMNAFDPSPGK1PGK2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278793-B1 | SCALE AND CORROSION INHIBITORS | RHODIA CONS SPEC LTD (GB) | 2005-01-05 | — | — | EP | claimed |
| CN-108658263-A | A kind of paint waste water treatment agents and preparation method thereof | 安徽康瑞高科新材料技术工程有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-105688680-A | Washing method for anti-osmosis film elements | 北京今大禹环境技术股份有限公司 | 2016-06-22 | — | — | CN | disclosed |