Naphthalene

Naphthalene

SCHEMBL9438226

O=P(O)(O)Oc1cccc(O)c1.c1ccc2ccccc2c1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.57
INPPL1 O15357 4/20 0.47
INPP5A Q14642 4/20 0.47
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 2/20 0.44
GPR84 Q9NQS5 2/20 0.43
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
INPP5B P32019 1/20 0.40
CETP P11597 1/20 0.40
CLK1 P49759 1/20 0.39
DYRK1A Q13627 1/20 0.39
DYRK1B Q9Y463 1/20 0.39
PTPN1 P18031 1/20 0.39
CA12 O43570 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CA2 P00918 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29743077 0.93 SRC (0.59) SRCINPPL1INPP5ACYP3A4ESR1
SCHEMBL133534 0.93 SRC (0.59) SRCINPPL1INPP5ACYP3A4ESR1
Phenol SCHEMBL999412 0.91 SRC (0.64) SRCINPPL1INPP5ACYP3A4ESR1
SCHEMBL20854529 0.91 SRC (0.58) SRCINPPL1INPP5ACYP3A4ESR1
Biphenyl SCHEMBL6141288 0.88 SRC (0.60) SRCINPPL1INPP5AHSD17B1HSD17B2
Phenyl Dihydrogen Phosphate SCHEMBL1457869 0.85 SRC (0.73) SRCINPPL1INPP5ACYP3A4INPP5B
Phenyl Dihydrogen Phosphate SCHEMBL6767193 0.85 SRC (0.73) SRCINPPL1INPP5ACYP3A4INPP5B
Phenyl Dihydrogen Phosphate SCHEMBL27723079 0.84 SRC (0.70) SRCINPPL1INPP5ACYP3A4INPP5B
SCHEMBL2423618 0.83 SRC (0.55) SRCINPPL1INPP5ACYP3A4ESR1
SCHEMBL5388501 0.81 SRC (0.49) SRCINPPL1INPP5AHSD17B2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54117401-A None JP disclosed
JP-61083196-A None JP disclosed
EP-0379999-B1 Polysaccharide, and water absorbent, moisture absorbent or humectant and thickening agent chiefly made of the polysaccharide, and cultivation method of producing it by a microorganism HAKUTO CORP (JP) 1994-12-21 EP disclosed
US-5175279-A Culture of Alcaligenes in sugar mixture HAKUTO CO., LTD. (JP) 1992-12-29 US disclosed
EP-0379999-A1 Polysaccharide, and water absorbent, moisture absorbent or humectant and thickening agent chiefly made of the polysaccharide, and cultivation method of producing it by a microorganism HAKUTO CORPORATION (JP) 1990-08-01 EP disclosed
EP-0122152-B1 ENZYMATIC PRODUCTION OF SPHINGOPHOSPHOLIPID DERIVATIVES MEITO SANGYO KABUSHIKI KAISHA (JP) 1989-03-22 EP disclosed
EP-0125039-B1 ENZYMATIC PRODUCTION OF PHOSPHOLIPID-SACCHARIDE DERIVATIVES MEITO SANGYO KABUSHIKI KAISHA (JP) 1989-02-15 EP disclosed
US-4782019-A ESTER INTERCHANGE, PHOSPHOLIPASE MEITO SANGYO KABUSHIKI KAISHA (JP) 1988-11-01 US disclosed
US-4624919-A Enzymatic production of phospholipid-saccharide derivatives MEITO SANGYO KABUSHIKI KAISHA (JP) 1986-11-25 US disclosed
JP-S6183196-A ANTIMYCOTIC BANYU PHARMACEUT CO LTD 1986-04-26 JP disclosed
JP-S54117401-A ANTIFUNGAL AGENT NEOENACTIN AND PREPARATION THEREOF BANYU PHARMACEUT CO LTD 1979-09-12 JP disclosed
JP-S06183196-A 0001-01-01 JP disclosed