Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.31 |
| ▸ | CES2 | O00748 | 3/20 | 0.31 |
| ▸ | CES1 | P23141 | 3/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141446 | 0.98 | TSHR (0.32) | TSHRTHRBSIRT2 | |
| SCHEMBL6141332 | 0.91 | — | — | |
| SCHEMBL4076165 | 0.80 | CETP (0.33) | — | |
| SCHEMBL23572529 | 0.77 | TSHR (0.36) | TSHRTHRBDNM1GAA | |
| SCHEMBL24308962 | 0.77 | TSHR (0.36) | TSHRTHRBDNM1GAA | |
| SCHEMBL3413093 | 0.74 | TSHR (0.35) | TSHRTHRBGAA | |
| SCHEMBL7879421 | 0.71 | — | — | |
| SCHEMBL4127259 | 0.70 | HSD11B1 (0.34) | — | |
| SCHEMBL22518978 | 0.70 | TSHR (0.33) | TSHRTHRBSIRT2GAA | |
| Decane SCHEMBL15911069 | 0.68 | TSHR (0.67) | TSHRTHRBCES2CES1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517881-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES | Syngenta Participations AG (CH) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004002943-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-08 | — | — | WO | disclosed |