SCHEMBL125940

SCHEMBL125940

CC(C)(CCCOCC1CO1)O[SiH3]

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
SMN1; SMN2 Q16637 1/20 0.55
ALDH1A1 P00352 5/20 0.51
TDP1 Q9NUW8 1/20 0.51
MAPK1 P28482 1/20 0.47
TP53 P04637 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
PPARG P37231 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153464 0.97 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17710340 0.95 TSHR (0.60) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL904731 0.89 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL614218 0.86 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL614178 0.82 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL12158820 0.82 TSHR (0.65) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL845307 0.81 TSHR (0.55) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4893329 0.81 TSHR (0.60) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4889891 0.81 TSHR (0.60) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL613049 0.81 TSHR (0.64) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 662 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025122886-A1 SYSTEMS FOR SUPERELASTIC SPLINES WITH POLYMER INSULATION ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. (US) 2025-06-12 WO claimed
US-20250154325-A1 VANILLIC ACID-BASED ORGANIC-INORGANIC COMPOUND, CURABLE COMPOSITION, AND PRODUCTION METHOD THEREOF ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2025-05-15 US claimed
US-20240299730-A1 POLYMER COATINGS FOR SHAPE MEMORY ALLOYS FOR USE IN PERCUTANEOUS HEART PUMPS TC1 LLC 2024-09-12 US claimed
US-12017056-B2 Polymer coatings for shape memory alloys for use in percutaneous heart pumps TC1 LLC (US) 2024-06-25 US claimed
US-11945993-B2 In-situ aerogel type hydraulic cement composition for subterranean applications HALLIBURTON ENERGY SERVICES, INC. (US) 2024-04-02 US claimed
US-20230391956-A1 SILYL ETHER ISOHEXIDE-BASED ORGANIC-INORGANIC COMPOUND, METHOD FOR PREPARING THE SAME, AND CURABLE COMPOSITION CONTAINING THE SAME ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2023-12-07 US claimed
CN-115651178-A Synthesis method of polyester with siloxane side group 新丰见微化工实业有限公司 2023-01-31 CN claimed
CN-111979765-B Preparation method of hydroxyl fiber with antibacterial function 苏州合祥纺织科技有限公司 2022-10-25 CN claimed
CN-113372827-A Special packaging adhesive film for heterojunction battery and preparation method thereof 浙江祥邦科技股份有限公司 2021-09-10 CN claimed
US-20210162200-A1 POLYMER COATINGS FOR SHAPE MEMORY ALLOYS FOR USE IN PERCUTANEOUS HEART PUMPS TC1 LLC (US) 2021-06-03 US claimed
WO-2004107053-A1 POSITIVE PHOTORESIST COMPOSITION FOR SPINLESS (SLIT) COATING ADMS TECHNOLOGY CO., LTD. (KR) 2004-12-09 WO claimed
WO-2004107052-A1 NEGATIVE PHOTORESIST COMPOSITION FOR SPINLESS (SLIT) COATING ADMS TECHNOLOGY CO., LTD. (KR) 2004-12-09 WO claimed
WO-2004097522-A1 NEGATIVE RESIST COMPOSITION FOR ORGANIC INSULATOR OF HIGH APERTURE LCD ADMS TECHNOLOGY CO. LTD. (KR) 2004-11-11 WO claimed
EP-1459067-A2 METHOD OF ATTACHMENT OF A BIOMOLECULE TO A SOLID SURFACE Amersham Biosciences UK Limited (GB) 2004-09-22 EP claimed
EP-1209492-B1 Formation of materials such as waveguides with a refractive index step NAT UNIV IRELAND CORK (IE) 2004-02-04 EP claimed
US-20030153777-A1 Amine compounds and curable compositions derived therefrom VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2003-08-14 US claimed
US-6545075-B2 Thermoplastic resin composition KUREHA KAGAKU KOGYO K.K. (JP) 2003-04-08 US claimed
WO-2003027677-A2 METHOD OF ATTACHMENT OF A BIOMOLECULE TO A SOLID SURFACE AMERSHAM BIOSCIENCES UK LIMITED (GB) 2003-04-03 WO claimed
US-20020107335-A1 Resin component containing a poly(arylene sulfide) and a polyamide-imide; and a silane compound containing a functional group selected from the group consisting of amino, ureido, epoxy, isocyanate and mercapto groups. KUREHA CORPORATION (JP) 2002-08-08 US claimed
EP-1033388-A1 THERMOPLASTIC RESIN COMPOSITION KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-09-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030153777-A1 Amine compounds and curable compositions derived therefrom NOTUM, HNMT, PNMT TSHR 4851/4885SMN1; SMN2 2560/4885ALDH1A1 259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.