Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.53 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2990653 | 0.99 | EGFR (0.59) | EGFRRGS12ALDH1A1LCKMAPT | |
| SCHEMBL6141584 | 0.89 | EGFR (0.45) | EGFRRGS12ALDH1A1LCKMAPT | |
| Hydrochloric Acid SCHEMBL2984737 | 0.88 | EGFR (0.44) | EGFRRGS12ALDH1A1LCKMAPT | |
| SCHEMBL7563737 | 0.83 | MAPT (0.47) | EGFRALDH1A1MAPTSYK | |
| SCHEMBL5898768 | 0.80 | HTR2C (0.46) | EGFRALDH1A1MAPTTDP1 | |
| SCHEMBL6141590 | 0.80 | MAPT (0.41) | EGFRMAPTNOX4 | |
| SCHEMBL6739725 | 0.80 | ADRA2B (0.37) | EGFRRGS12ALDH1A1LCKMAPT | |
| Hydrochloric Acid SCHEMBL2993181 | 0.79 | EGFR (0.62) | EGFRRGS12ALDH1A1LCKMAPT | |
| Hydrochloric Acid SCHEMBL2981450 | 0.78 | MAPT (0.40) | EGFRMAPTNOX4 | |
| Hydrochloric Acid SCHEMBL6271307 | 0.78 | ADRA2B (0.36) | EGFRMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493731-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and these derivatives | Wella Aktiengesellschaft (DE) | 2005-01-05 | — | — | EP | disclosed |