Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.45 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2984737 | 0.99 | EGFR (0.44) | EGFRRGS12ALDH1A1LCKMAPT | |
| SCHEMBL6739725 | 0.91 | ADRA2B (0.37) | EGFRRGS12ALDH1A1LCKMAPT | |
| Hydrochloric Acid SCHEMBL6271307 | 0.90 | ADRA2B (0.36) | EGFRMAPTTDP1 | |
| SCHEMBL6141925 | 0.89 | EGFR (0.60) | EGFRRGS12ALDH1A1LCKMAPT | |
| Hydrochloric Acid SCHEMBL2990653 | 0.88 | EGFR (0.59) | EGFRRGS12ALDH1A1LCKMAPT | |
| Hydrochloric Acid SCHEMBL6740557 | 0.84 | ADRA2B (0.33) | — | |
| SCHEMBL6739060 | 0.83 | ADRA2B (0.38) | EGFRMAPT | |
| SCHEMBL6141858 | 0.81 | ARG1 (0.39) | ALDH1A1MAPT | |
| SCHEMBL6734684 | 0.81 | EGFR (0.44) | EGFRRGS12ALDH1A1LCKMAPT | |
| SCHEMBL7158153 | 0.81 | ARG1 (0.56) | EGFRRGS12ALDH1A1LCKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493731-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and these derivatives | Wella Aktiengesellschaft (DE) | 2005-01-05 | — | — | EP | disclosed |