Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 14/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62618 | 0.85 | INSR (0.52) | INSRMEN1KMT2AALDH1A1APP | |
| SCHEMBL60940 | 0.84 | INSR (0.49) | INSRMEN1KMT2AALDH1A1APP | |
| SCHEMBL62493 | 0.84 | INSR (0.49) | INSRMEN1KMT2AALDH1A1APP | |
| SCHEMBL61437 | 0.82 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1USP2HPGD | |
| SCHEMBL13232760 | 0.79 | INSR (0.43) | INSRMEN1KMT2AALDH1A1APP | |
| SCHEMBL62438 | 0.78 | INSR (0.42) | INSRMEN1KMT2AALDH1A1APP | |
| SCHEMBL61558 | 0.78 | INSR (0.42) | INSRMEN1KMT2AALDH1A1APP | |
| SCHEMBL61398 | 0.78 | INSR (0.42) | INSRMEN1KMT2AALDH1A1APP | |
| SCHEMBL61009 | 0.76 | INSR (0.42) | INSRMEN1KMT2AALDH1A1APP | |
| SCHEMBL62459 | 0.71 | INSR (0.47) | INSRMEN1KMT2AALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129525-B2 | Long wavelength thiol-reactive fluorophores | BECTON DICKINSON AND COMPANY (US) | 2012-03-06 | — | — | US | disclosed |
| US-8071794-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON AND COMPANY (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2011-07-28 | — | — | US | disclosed |
| US-7767821-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2010-08-03 | — | — | US | disclosed |
| US-7767821-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100167417-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100167417-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100003763-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2010-01-07 | — | — | US | disclosed |
| US-7563891-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2009-07-21 | — | — | US | disclosed |
| US-7563891-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2009-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167417-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | INSR 4540/4885MEN1 4815/4885KMT2A 3702/4885 |
| US-20100003763-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | INSR 4540/4885MEN1 4815/4885KMT2A 3702/4885 |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | INSR 4540/4885MEN1 4815/4885KMT2A 3702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.