Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6143512 | 1.00 | ESR1 (0.59) | ESR1ESR2 | |
| SCHEMBL6143511 | 1.00 | ESR1 (0.59) | ESR1ESR2 | |
| SCHEMBL6142894 | 0.87 | ESR1 (0.52) | ESR1ESR2 | |
| SCHEMBL6142890 | 0.87 | ESR1 (0.52) | ESR1ESR2 | |
| SCHEMBL6142892 | 0.87 | ESR1 (0.52) | ESR1ESR2 | |
| SCHEMBL7580211 | 0.84 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL6143036 | 0.80 | ESR1 (0.53) | ESR1ESR2 | |
| SCHEMBL7582587 | 0.79 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL7573215 | 0.78 | ESR1 (0.53) | ESR1ESR2 | |
| SCHEMBL7582157 | 0.77 | ESR1 (0.49) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951883-B2 | 2H-1-benzopyran derivatives processes for their preparation and pharmaceutical compositions thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2005-10-04 | — | — | US | disclosed |
| EP-1355906-B1 | 2H-1-BENZOPYRAN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | CHIESI FARMA SPA (IT) | 2005-01-12 | — | — | EP | disclosed |
| US-20040106595-A1 | 2H-1-benzopyran derivatives processes for their preparation and pharmaceutical compositions thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2004-06-03 | — | — | US | disclosed |
| EP-1229036-A1 | 2H-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof | CHIESI FARMACEUTICI S.p.A. (IT) | 2002-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106595-A1 | 2H-1-benzopyran derivatives processes for their preparation and pharmaceutical compositions thereof | CYP19A1, BRCA1, HPD | ESR1 16/4885ESR2 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.