Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SI | P14410 | 2/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478060 | 0.87 | ALDH1A1 (0.33) | ALDH1A1TET2EGLN1TSHR | |
| SCHEMBL120572 | 0.82 | — | — | |
| SCHEMBL7068975 | 0.80 | — | — | |
| SCHEMBL29057321 | 0.80 | — | — | |
| SCHEMBL2821588 | 0.76 | SOAT1 (0.48) | ALDH1A1EGLN1TSHRMGAMGAA | |
| SCHEMBL9788303 | 0.76 | GAA (0.48) | ALDH1A1TET2EGLN1TSHRMGAM | |
| SCHEMBL8832445 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TET2EGLN1TSHRMGAM | |
| SCHEMBL13009507 | 0.75 | FFAR3 (0.47) | ALDH1A1TSHRTDP1FFAR3SOAT1 | |
| SCHEMBL5352787 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TET2EGLN1TSHRMGAM | |
| SCHEMBL30831806 | 0.75 | FFAR3 (0.47) | ALDH1A1TSHRTDP1FFAR3SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585733-A1 | HETEROCYCLIC PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004063166-A1 | HETEROCYCLIC PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |