Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.54 |
| ▸ | RXRB | P28702 | 7/20 | 0.54 |
| ▸ | RARB | P10826 | 12/20 | 0.46 |
| ▸ | RARG | P13631 | 12/20 | 0.46 |
| ▸ | RARA | P10276 | 9/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6144896 | 1.00 | RXRA (0.54) | RXRARXRBRARBRARGRARA | |
| SCHEMBL29743366 | 0.83 | RXRA (0.38) | RXRARXRBRARBRARGRARA | |
| SCHEMBL6554250 | 0.83 | RXRA (0.38) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7896493 | 0.83 | RXRA (0.50) | RXRARXRBRARBRARGRARA | |
| SCHEMBL29638129 | 0.82 | RXRA (0.38) | RXRARXRBRARBRARGRARA | |
| SCHEMBL3819800 | 0.81 | RXRA (0.49) | RXRARXRBRARBRARGRARA | |
| SCHEMBL6146723 | 0.80 | RXRA (0.48) | RXRARXRBRARBRARGRARA | |
| SCHEMBL6146729 | 0.80 | RXRA (0.48) | RXRARXRBRARBRARGRARA | |
| SCHEMBL3175854 | 0.80 | RXRA (0.57) | RXRARXRBRARBRARGRARA | |
| SCHEMBL8529271 | 0.79 | RXRA (0.57) | RXRARXRBRARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280757-B1 | NEW GAMMA SELECTIVE RETINOIDS | HOFFMANN LA ROCHE (CH) | 2005-08-17 | — | — | EP | disclosed |