Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.57 |
| ▸ | RXRB | P28702 | 6/20 | 0.57 |
| ▸ | RARA | P10276 | 8/20 | 0.52 |
| ▸ | RARB | P10826 | 8/20 | 0.52 |
| ▸ | RARG | P13631 | 8/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.50 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897270 | 0.82 | RXRA (0.47) | RXRARXRBRARARARBRARG | |
| SCHEMBL6146556 | 0.79 | RARB (0.78) | RXRARXRBRARARARBRARG | |
| SCHEMBL6145030 | 0.79 | RARB (0.78) | RXRARXRBRARARARBRARG | |
| SCHEMBL6144896 | 0.79 | RXRA (0.54) | RXRARXRBRARARARBRARG | |
| SCHEMBL6144891 | 0.79 | RXRA (0.54) | RXRARXRBRARARARBRARG | |
| SCHEMBL6143604 | 0.77 | RXRA (0.64) | RXRARXRBRARARARBRARG | |
| SCHEMBL6143601 | 0.77 | RXRA (0.64) | RXRARXRBRARARARBRARG | |
| SCHEMBL8458521 | 0.76 | RXRA (0.66) | RXRARXRBRARARARBRARG | |
| SCHEMBL8458523 | 0.76 | RXRA (0.66) | RXRARXRBRARARARBRARG | |
| SCHEMBL7756578 | 0.76 | RXRA (0.58) | RXRARXRBRARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915823-A1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998022423-A1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-05-28 | — | — | WO | disclosed |