Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3317863 | 0.86 | ITGB1 (0.53) | ITGB1ITGAVITGA4ALDH1A1L3MBTL1 | |
| SCHEMBL4410500 | 0.86 | ITGB1 (0.53) | ITGB1ITGAVITGA4ALDH1A1L3MBTL1 | |
| SCHEMBL4625418 | 0.83 | ITGB1 (0.44) | ITGB1ITGAVITGA4MAPTALDH1A1 | |
| SCHEMBL3314360 | 0.79 | ITGB1 (0.48) | ITGB1ITGAVITGA4ALDH1A1L3MBTL1 | |
| SCHEMBL6142066 | 0.79 | ITGB1 (0.45) | ITGB1ITGAVITGA4MAPTALDH1A1 | |
| SCHEMBL3320849 | 0.75 | ITGB1 (0.56) | ITGB1ITGAVITGA4ALDH1A1L3MBTL1 | |
| SCHEMBL3318694 | 0.74 | ITGB1 (0.45) | ITGB1ITGAVITGA4ALDH1A1ITGB7 | |
| SCHEMBL4625253 | 0.74 | ITGB1 (0.43) | ITGB1ITGAVITGA4ALDH1A1ITGB7 | |
| SCHEMBL3313128 | 0.74 | ITGB1 (0.43) | ITGB1ITGAVITGA4ALDH1A1ITGB7 | |
| SCHEMBL6140359 | 0.72 | ITGB1 (0.55) | ITGB1ITGAVITGA4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501801-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | UCB, S.A. (BE) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093237-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | UCB, S.A. (BE) | 2003-11-13 | — | — | WO | claimed |
| EP-1501801-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | UCB, S.A. (BE) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093237-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | UCB, S.A. (BE) | 2003-11-13 | — | — | WO | disclosed |