Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TTK | P33981 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377854 | 1.00 | KDM4E (0.58) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL38660856 | 0.88 | KDM4E (0.47) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL1023212 | 0.85 | CYP1A2 (0.63) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| Tert-Butyl Formate SCHEMBL28740575 | 0.80 | CYP1A2 (0.41) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL1672674 | 0.75 | IDO1 (0.78) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL29481432 | 0.73 | PDPK1 (1.00) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL9407409 | 0.73 | KDM4E (0.60) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL18878 | 0.73 | PDPK1 (1.00) | KDM4EGAAPDPK1CYP3A4IDO1 | |
| SCHEMBL30855645 | 0.73 | PDPK1 (0.68) | PDPK1HPGDLRRK2CDK2FLT3 | |
| SCHEMBL4060640 | 0.73 | ATM (0.57) | KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 724 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036679-A | Preparation method and application of indazole carboxylic acid | 广东大丰植保科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-119059958-A | Method for aryl debromination acylation of bromobenzazepine compounds | 上海沃凯生物技术有限公司 | 2024-12-03 | — | — | CN | claimed |
| WO-2024193328-A1 | INDAZOLE SUBSTITUTED PODOPHYLLOTOXIN DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 汤亚杰 | 2024-09-26 | — | — | WO | claimed |
| WO-2021070416-A1 | THERMOSETTING RESIN COMPOSITION, CURED PRODUCT THEREOF, AND STRUCTURAL BODY INCLUDING SAID CURED PRODUCT | 昭和電工株式会社 | 2021-04-15 | — | — | WO | claimed |
| EP-2812332-B1 | METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND | VIIV HEALTHCARE UK (NO 4) LTD (GB) | 2017-08-09 | — | — | EP | claimed |
| WO-2016183101-A1 | PALLADIUM-CATALYZED ARYLATION OF FLUOROALKYLAMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-11-17 | — | — | WO | claimed |
| CN-104080785-B | For the method preparing HIV attachment inhibitor piperazine prodrug compound | 百时美施贵宝公司 | 2016-08-31 | — | — | CN | claimed |
| US-9249168-B2 | Methods for the preparation of HIV attachment inhibitor piperazine prodrug compound | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-02-02 | — | — | US | claimed |
| US-20150038711-A1 | METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND | VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) | 2015-02-05 | — | — | US | claimed |
| EP-2812332-A1 | METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND | Bristol-Myers Squibb Company (US) | 2014-12-17 | — | — | EP | claimed |
| CN-104080785-A | Methods for the preparation of hiv attachment inhibitor piperazine prodrug compound | SQUIBB BRISTOL MYERS COMPANY | 2014-10-01 | — | — | CN | claimed |
| WO-2013119625-A1 | METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-08-15 | — | — | WO | claimed |
| US-20130203992-A1 | METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-08-08 | — | — | US | claimed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | claimed |
| CN-122060008-A | Indazole alkaloid derivative and preparation method and application thereof | 江西师范大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-122036679-A | Preparation method and application of indazole carboxylic acid | 广东大丰植保科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-122036679-A | Preparation method and application of indazole carboxylic acid | 广东大丰植保科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-0683155-A1 | Tetrahydrobenz cd indoles with serotonin regulatory activity | ELI LILLY AND COMPANY (US) | 1995-11-22 | — | — | EP | disclosed |
| US-5385928-A | Antiserotonine agent | ELI LILLY AND COMPANY (US) | 1995-01-31 | — | — | US | disclosed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203992-A1 | METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND | FURIN, NAPA, PREP | KDM4E 1563/4885GAA 1596/4885PDPK1 2903/4885 |
| US-20150038711-A1 | METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND | FURIN, NAPA, PREP | KDM4E 1563/4885GAA 1596/4885PDPK1 2903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.