Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | TTK | P33981 | 2/20 | 0.78 |
| ▸ | ALPL | P05186 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.78 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.64 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | ITK | Q08881 | 4/20 | 0.60 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.60 |
| ▸ | FLT1 | P17948 | 1/20 | 0.60 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30768403 | 0.88 | ALDH1A1 (1.00) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL855531 | 0.88 | ALDH1A1 (1.00) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL3712544 | 0.87 | KDM4E (0.62) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL4796146 | 0.85 | KDM4E (0.66) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL17178615 | 0.84 | ALDH1A1 (0.92) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL1287897 | 0.83 | LRRK2 (0.68) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL10533662 | 0.83 | IDO1 (0.74) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL10452107 | 0.82 | LRRK2 (0.62) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL16937122 | 0.81 | IDO1 (0.71) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL4480025 | 0.81 | ALDH1A1 (0.71) | IDO1KDM4EGAAALDH1A1TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132123-A1 | ABAD INHIBITOR COMPOUNDS | UNIV COURT OF THE UNIV OF ST ANDREWS (GB) | 2026-05-14 | — | — | US | disclosed |
| US-12171665-B2 | Compression resistant implants including an oxysterol and methods of use | WARSAW ORTHOPEDIC, INC. (US) | 2024-12-24 | — | — | US | disclosed |
| US-12171909-B2 | Implants having a drug load of an oxysterol and methods of use | WARSAW ORTHOPEDIC, INC. (US) | 2024-12-24 | — | — | US | disclosed |
| EP-4392412-A1 | ABAD INHIBITOR COMPOUNDS | University Court of The University of St Andrews (GB) | 2024-07-03 | — | — | EP | disclosed |
| US-20230166003-A1 | IMPLANTS HAVING A DRUG LOAD OF AN OXYSTEROL AND METHODS OF USE | WARSAW ORTHOPEDIC, INC. (US) | 2023-06-01 | — | — | US | disclosed |
| WO-2023026060-A1 | ABAD INHIBITOR COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2023-03-02 | — | — | WO | disclosed |
| US-11464888-B2 | Moldable formulations containing an oxysterol in an acellular tissue matrix | WARSAW ORTHOPEDIC, INC. (US) | 2022-10-11 | — | — | US | disclosed |
| EP-3617217-B1 | PROCESS FOR THE PRODUCTION OF OXYSTEROLS | WARSAW ORTHOPEDIC INC (US) | 2022-09-07 | — | — | EP | disclosed |
| US-11384114-B2 | Polymorphic forms of an oxysterol and methods of making them | WARSAW ORTHOPEDIC, INC. (US) | 2022-07-12 | — | — | US | disclosed |
| EP-3827833-B1 | METHODS FOR THE SEPARATION AND DETECTION OF AN OXYSTEROL | WARSAW ORTHOPEDIC INC (US) | 2022-06-15 | — | — | EP | disclosed |
| US-6811979-B2 | NUCLEOTIDE DERIVATIVE FOR USE IN SEQUENCE DETERMINATION OF NUCLEIC ACID MOLECULE | APPLERA CORPORATION | 2004-11-02 | — | — | US | disclosed |
| EP-1141137-B1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | APPLERA CORP (US) | 2003-10-08 | — | — | EP | disclosed |
| EP-1317464-A2 | FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS | Applera Corporation (US) | 2003-06-11 | — | — | EP | disclosed |
| US-20030055257-A1 | Water-soluble rhodamine dye conjugates | APPLERA CORPORATION (US) | 2003-03-20 | — | — | US | disclosed |
| US-20020102590-A1 | Fluorescent nucleobase conjugates having anionic linkers | PE CORPORATION (NY) (US) | 2002-08-01 | — | — | US | disclosed |
| WO-2002030944-A2 | FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS | APPLERA CORPORATION (US) | 2002-04-18 | — | — | WO | disclosed |
| US-6372907-B1 | LABELLED RHODAMINE DYE-POLYPEPTIDE CONJUGATE, OR SALT THEREOF, COMPRISING RHODAMINE-TYPE PARENT XANTHENE RING SUBSTITUTED AT XANTHENE C-9 CARBON WITH SUBSTITUTED PHENYL RING | APPTERA CORPORATION | 2002-04-16 | — | — | US | disclosed |
| EP-1141137-A1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | Applera Corporation (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001032783-A1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | APPLERA CORPORATION (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6191278-B1 | COMPRISING A RHODAMINE-TYPE PARENT RING HAVING ATTACHED TO THE XANTHENE C9 CARBON A PHENYL GROUP THAT IS SUBSTITUTED WITH CARBOXY OR SULFONATE GROUP, ONE TO THREE AMINOPYRIDINIUM GROUPS AND AN ALKYL- OR ARYLTHIO, AND OPTIONALLY OTHER GROUPS | PE CORPORATION | 2001-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12171909-B2 | Implants having a drug load of an oxysterol and methods of use | SOST, CYP17A1, HSD17B7 | IDO1 1997/4885KDM4E 416/4885GAA 2568/4885 |
| US-20230166003-A1 | IMPLANTS HAVING A DRUG LOAD OF AN OXYSTEROL AND METHODS OF USE | SOST, CYP17A1, HSD17B7 | IDO1 1997/4885KDM4E 416/4885GAA 2568/4885 |
| US-20260132123-A1 | ABAD INHIBITOR COMPOUNDS | ADH1C, ADH1A, CBR1 | IDO1 860/4885KDM4E 2890/4885GAA 2008/4885 |
| US-11384114-B2 | Polymorphic forms of an oxysterol and methods of making them | HSD3B1, VKORC1L1, VKORC1 | IDO1 4397/4885KDM4E 4551/4885GAA 4522/4885 |
| US-20030055257-A1 | Water-soluble rhodamine dye conjugates | SLC43A3, ABCG2, TARBP1 | IDO1 4594/4885KDM4E 4494/4885GAA 1611/4885 |
| US-20020102590-A1 | Fluorescent nucleobase conjugates having anionic linkers | DNTT, DUT, NT5C3B | IDO1 4101/4885KDM4E 1295/4885GAA 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.