Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 3/20 | 0.37 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639283 | 0.91 | FYN (0.45) | MAPTKDM4EALDH1A1FYNROR1 | |
| SCHEMBL30926051 | 0.91 | MAPT (0.47) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL2176515 | 0.91 | FYN (0.45) | MAPTKDM4EALDH1A1FYNROR1 | |
| SCHEMBL152145 | 0.91 | MAPT (0.47) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL6952285 | 0.89 | MAPT (0.46) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL16925411 | 0.85 | MAPT (0.48) | MAPTKDM4EALDH1A1FYNROR1 | |
| SCHEMBL31253956 | 0.84 | PIK3CD (0.41) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL29924000 | 0.84 | SLC6A4 (0.40) | MAPTKDM4EALDH1A1SMN1; SMN2SLC6A4 | |
| SCHEMBL17386359 | 0.84 | MAOB (0.50) | MAPTSMN1; SMN2HDAC6CYP2C19HIF1A | |
| SCHEMBL19617265 | 0.83 | SCD (0.33) | PIK3CDABL1EGFRHCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698520-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | Gandeeva Therapeutics, Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220708-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | GANDEEVA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| US-20160207943-A1 | Apparatus and Methods for the Automated Synthesis of Small Molecules | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-21 | — | — | US | disclosed |
| EP-3018136-A1 | APPARATUS AND METHODS FOR THE AUTOMATED SYNTHESIS OF SMALL MOLECULES | The Board of Trustees of the University of Illionis (US) | 2016-05-11 | — | — | EP | disclosed |
| EP-2596000-B1 | APPARATUS AND METHODS FOR THE AUTOMATED SYNTHESIS OF SMALL MOLECULES | UNIV ILLINOIS (US) | 2016-04-20 | — | — | EP | disclosed |
| US-9238597-B2 | Apparatus and methods for the automated synthesis of small molecules | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-01-19 | — | — | US | disclosed |
| CN-102238948-B | Novel 4-(heterocycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and also in cosmetics | GALDERMA RES & DEV | 2015-03-25 | — | — | CN | disclosed |
| EP-2529735-B1 | COMPOSITIONS COMPRISING 4-(HETEROCYCLOALKYL)BENZENE-1,3-DIOL DERIVATIVES WITH TYROSINASE ENZYME INHIBITING ACTIVITY | GALDERMA RES & DEV (FR) | 2014-06-25 | — | — | EP | disclosed |
| EP-2529735-B1 | COMPOSITIONS COMPRISING 4-(HETEROCYCLOALKYL)BENZENE-1,3-DIOL DERIVATIVES WITH TYROSINASE ENZYME INHIBITING ACTIVITY | GALDERMA RES & DEV (FR) | 2014-06-25 | — | — | EP | disclosed |
| US-20130243670-A1 | Apparatus and Methods for the Automated Synthesis of Small Molecules | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2013-09-19 | — | — | US | disclosed |
| EP-1318974-A2 | RESORCINOL DERIVATIVES | Pfizer Products Inc. (US) | 2003-06-18 | — | — | EP | disclosed |
| US-6541473-B2 | Use as skin lightening agents; 4-(1,4-Dioxaspiro(4.5)dec-8-yl)-1,3-benzenediol for example | WARNER LAMBERT COMPANY | 2003-04-01 | — | — | US | disclosed |
| US-20020161041-A1 | Resorcinol derivatives | PFIZER INC. | 2002-10-31 | — | — | US | disclosed |
| US-20020155075-A1 | For use as topical depigmention agents that have good efficacy and are harmless | COLLINGTON ERIC WILLIAM (GB) | 2002-10-24 | — | — | US | disclosed |
| US-20020137961-A1 | Resorcinol derivatives | PFIZER INC. | 2002-09-26 | — | — | US | disclosed |
| WO-2002024613-A2 | RESORCINOL DERIVATIVES | PFIZER PRODUCTS, INC. (US) | 2002-03-28 | — | — | WO | disclosed |
| EP-1165031-A1 | RESORCINOL COMPOSITION | PFIZER INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | disclosed |
| WO-2000056279-A1 | RESORCINOL COMPOSITION | PFIZER INC. (US) | 2000-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130243670-A1 | Apparatus and Methods for the Automated Synthesis of Small Molecules | PCNA, BLK, FAR1 | PIK3CD 1493/4885ABL1 239/4885EGFR 500/4885 |
| US-20020155075-A1 | For use as topical depigmention agents that have good efficacy and are harmless | TYR, QDPR, DBH | PIK3CD 4348/4885ABL1 2920/4885EGFR 4591/4885 |
| US-20160207943-A1 | Apparatus and Methods for the Automated Synthesis of Small Molecules | PCNA, BLK, FAR1 | PIK3CD 1493/4885ABL1 239/4885EGFR 500/4885 |
| US-20020161041-A1 | Resorcinol derivatives | NQO1, LRAT, ALDH1A2 | PIK3CD 1663/4885ABL1 4363/4885EGFR 4367/4885 |
| US-20020137961-A1 | Resorcinol derivatives | LRAT, NQO1, ALDH1A2 | PIK3CD 1499/4885ABL1 4354/4885EGFR 4279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.