SCHEMBL6146099

SCHEMBL6146099

FC1=C(F)C(F)(F)c2cccc3ccc(F)c1c23

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
CYP1B1 Q16678 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PDK2 Q15119 1/20 0.33
AKR1A1 P14550 1/20 0.32
AKR1B1 P15121 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22223103 0.69 TSHR (0.40) TSHRALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL4296137 0.62 ALDH1A1 (0.55) TSHRALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL7560734 0.61 ALDH1A1 (0.56) TSHRALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL15847664 0.59 TYMS (0.52) TSHRALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL20967315 0.59 TSHR (0.43) TSHRALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL6283740 0.59 PDK2 (0.33) PDK2AKR1A1AKR1B1
SCHEMBL18318553 0.58 ALDH1A1 (0.37) TSHRALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL1533917 0.58 ALDH1A1 (0.48) TSHRALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL24785178 0.58 ALDH1A1 (0.43) TSHRALDH1A1CYP1A1CYP1A2CYP3A4
SCHEMBL20967314 0.58 ALDH1A1 (0.43) TSHRALDH1A1CYP1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1259553-B1 HIGH ACTIVITY CARBENIUM-ACTIVATED POLYMERIZATION CATALYSTS EXXONMOBIL CHEM PATENTS INC (US) 2005-01-12 EP claimed
EP-4087006-B1 LITHIUM-ION BATTERY AND ELECTRICAL APPARATUS INCLUDING THE SAME CONTEMPORARY AMPEREX TECHNOLOGY CO LTD (CN) 2023-05-24 EP disclosed
EP-4033579-B1 LITHIUM ION BATTERY AND RELEVANT BATTERY MODULE, BATTERY PACK AND APPARATUS CONTEMPORARY AMPEREX TECHNOLOGY CO LTD (CN) 2023-05-03 EP disclosed
CN-113690481-B Lithium ion battery and electric equipment comprising same 宁德时代新能源科技股份有限公司 2022-08-05 CN disclosed
US-11329319-B2 Lithium-ion battery and electrical apparatus including the same CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2022-05-10 US disclosed
EP-3799185-B1 LITHIUM ION BATTERY, AND BATTERY MODULE, BATTERY PACK AND DEVICE RELATED THERETO CONTEMPORARY AMPEREX TECHNOLOGY CO LTD (CN) 2022-05-04 EP disclosed
US-11196086-B2 Lithium ion battery and relevant battery module, battery pack and apparatus CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2021-12-07 US disclosed
CN-113690481-A Lithium ion battery and electric equipment comprising same 宁德时代新能源科技股份有限公司 2021-11-23 CN disclosed
CN-110323487-B Lithium ion battery and electric equipment comprising same 宁德时代新能源科技股份有限公司 2021-09-21 CN disclosed
US-20210119258-A1 LITHIUM-ION BATTERY AND ELECTRICAL APPARATUS INCLUDING THE SAME CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2021-04-22 US disclosed
US-9920067-B2 Bis-thienobenzothienothiophene compounds and process for their preparation ENI S.P.A. (IT) 2018-03-20 US disclosed
US-20170342087-A1 BIS-THIENOBENZOTHIENOTHIPOHENE COMPOUNDS AND PROCESS FOR THEIR PREPARATION Eni S.p.A.it (IT) 2017-11-30 US disclosed
EP-3230291-A1 BIS-THIENOBENZOTHIENOTHIOPHENE COMPOUNDS AND PROCESS FOR THEIR PREPARATION Eni .p.a. (IT) 2017-10-18 EP disclosed
WO-2016092065-A1 BIS-THIENOBENZOTHIENOTHIOPHENE COMPOUNDS AND PROCESS FOR THEIR PREPARATION ENI .P.A. (IT) 2016-06-16 WO disclosed
US-9150696-B2 Process for the preparation of polymers containing benzohetero [1,3] diazole units ENI S.P.A. (IT) 2015-10-06 US disclosed
US-20140235818-A1 PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING BENZOHETERO [1,3] DIAZOLE UNITS ENI S.P.A. (IT) 2014-08-21 US disclosed
EP-2755752-A1 SORBENT COMPRISING CROSSLINKED POLYVINYLAMINE ON ITS SURFACE FOR THE PURIFICATION OF ORGANIC MOLECULES InstrAction GmbH (DE) 2014-07-23 EP disclosed
EP-2742080-A1 PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING BENZOHETERO [1, 3]DIAZOLE UNITS ENI S.p.A. (IT) 2014-06-18 EP disclosed
WO-2013037991-A1 SORBENT COMPRISING CROSSLINKED POLYVINYLAMINE ON ITS SURFACE FOR THE PURIFICATION OF ORGANIC MOLECULES INSTRACTION GMBH (DE) 2013-03-21 WO disclosed
WO-2013021314-A1 PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING BENZOHETERO [1, 3] DIAZOLE UNITS ENI S.P.A. (IT) 2013-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170342087-A1 BIS-THIENOBENZOTHIENOTHIPOHENE COMPOUNDS AND PROCESS FOR THEIR PREPARATION TST, DUS2, DDT TSHR 2373/4885ALDH1A1 815/4885CYP1A1 1932/4885
US-11196086-B2 Lithium ion battery and relevant battery module, battery pack and apparatus CACNA2D1, CLCN2, CACNA2D2 TSHR 3771/4885ALDH1A1 2608/4885CYP1A1 4269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.