SCHEMBL6147342

SCHEMBL6147342

CCOC(=O)NOC(=O)CC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.44
MGAM O43451 2/20 0.44
SI P14410 2/20 0.44
MGAM2 Q2M2H8 2/20 0.44
ALDH1A1 P00352 4/20 0.41
LMNA P02545 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ALOX15 P16050 1/20 0.39
TRPA1 O75762 1/20 0.37
CYP1A2 P05177 2/20 0.36
SOAT1 P35610 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 2/20 0.33
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18445858 0.83 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL28268550 0.81 GAA (0.46) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL179862 0.80 ALDH1A1 (0.52) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL27736872 0.79 ALDH1A1 (0.44) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7942127 0.79 CYP1A2 (0.50) GAAMGAMSIMGAM2ALDH1A1
Urethane SCHEMBL5961644 0.79 ALOX15 (0.56) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL136487 0.78 ALDH1A1 (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL11239491 0.78 GAA (0.43) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL1331762 0.77
SCHEMBL15500 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110484190-A Caravan vehicle body solvent-free single-component moisture cure urethanes adhesive and preparation method thereof SHANXI RES INSTITUTE OF APPLIED CHEMISTRY COMPANY LIMITED 2019-11-22 CN disclosed
CN-101067024-B Method for preparing organic silicon compound with beta-keto carbonyl group function WAKE CHEMIE INC 2012-08-08 CN disclosed
CN-100512599-C Board for printed wiring and printed wiring board SUMITOMO ELECTRIC INDUSTRIES (JP) 2009-07-08 CN disclosed
CN-101252814-A Wiring substrate SANYO ELECTRIC CO (JP) 2008-08-27 CN disclosed
CN-100390980-C Signal line circuit device SANYO ELECTRIC CO (JP) 2008-05-28 CN disclosed
CN-100351972-C Supporting structure of fixed contact terminals OMRON TATEISI ELECTRONICS CO (JP) 2007-11-28 CN disclosed
CN-101067024-A Method for preparing organic silicon compound with beta-keto carbonyl group function WAKE CHEMIE INC (DE) 2007-11-07 CN disclosed
EP-1280842-B1 AQUEOUS TWO-COMPONENT CROSS-LINKABLE COMPOSITION AKZO NOBEL COATINGS INT BV (NL) 2005-11-02 EP disclosed
CN-1661854-A Signal line circuit device SANYO ELECTRIC CO (JP) 2005-08-31 CN disclosed
CN-1659938-A Board for printed wiring, printed wiring board, and method for manufacturing them SUMITOMO ELECTRIC INDUSTRIES (JP) 2005-08-24 CN disclosed
CN-1637992-A Supporting structure of fixed contact terminals OMRON TATEISI ELECTRONICS CO (JP) 2005-07-13 CN disclosed
EP-1280842-A1 AQUEOUS TWO-COMPONENT CROSS-LINKABLE COMPOSITION Akzo Nobel N.V. (NL) 2003-02-05 EP disclosed
CN-1380166-A Banana tree pseudobark laminated board and its preparation process LUO LAIREN (CN) 2002-11-20 CN disclosed
US-6479151-B2 DISPERSION OF A PARTIALLY NEUTRALIZED AMINO-FUNCTIONAL EPOXY DERIVED POLYMER AND A COMPOUND WITH AT LEAST TWO ACETOACETATE GROUPS AND/OR ACETOACETAMIDE GROUPS; COATINGS WITH HARDNESS, GLOSS, WATER AND SOLVENT RESISTANCE; ADHESIVE STRENGTH AKZO NOBEL, N.V. (NL) 2002-11-12 US disclosed
US-20010056137-A1 Aqueous two-component cross-linkable composition AKZO NOBEL N.V. (NL) 2001-12-27 US disclosed
WO-2001077202-A1 AQUEOUS TWO-COMPONENT CROSS-LINKABLE COMPOSITION AKZO NOBEL N.V. (NL) 2001-10-18 WO disclosed
US-5288804-A Curable coating and film compositions comprising addition or condensation polymers; low water reactivity of aldimine allows crosslinking of aqueous polymer dispersion; quality REICHHOLD CHEMICALS, INC. (US) 1994-02-22 US disclosed
EP-0552469-A2 Acetoacetate aromatic aldimine resin composition REICHHOLD CHEMICALS, INC. (US) 1993-07-28 EP disclosed