SCHEMBL6147883

SCHEMBL6147883

CC(C)C1=Cc2c(cccc2-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)C1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
HTR1A P08908 1/20 0.32
HTR7 P34969 1/20 0.32
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PLA2G1B P04054 1/20 0.30
NFKB1 P19838 1/20 0.30
CASP3 P42574 1/20 0.30
RAB9A P51151 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ATG4B Q9Y4P1 1/20 0.30
PTAFR P25105 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30338635 1.00 RXRA (0.33) RXRARXRBHTR1AHTR7NPC1
SCHEMBL6148287 0.99 RXRA (0.32) RXRARXRBHTR1AHTR7
SCHEMBL29534991 0.87 BRD4 (0.34) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL1808402 0.87 BRD4 (0.34) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL6031753 0.82 RXRB (0.36) RXRARXRBHTR1AHTR7NPC1
SCHEMBL29594786 0.82 RXRB (0.36) RXRARXRBHTR1AHTR7NPC1
SCHEMBL6032314 0.81 BRD4 (0.32) ALDH1A1
SCHEMBL6150740 0.81 RXRB (0.35) RXRARXRBHTR1AHTR7PTAFR
SCHEMBL16394544 0.80 RXRA (0.34) RXRARXRBHTR1AHTR7PTAFR
SCHEMBL6149919 0.80 BRD4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240294680-A1 Polyethylene and Its Chlorinated Polyethylene LG CHEM, LTD. (KR) 2024-09-05 US disclosed
US-12006378-B2 Polyethylene and its chlorinated polyethylene LG CHEM, LTD. (KR) 2024-06-11 US disclosed
US-11993665-B2 Hybrid supported catalyst and method of preparing polyolefin using the same LG CHEM, LTD. (KR) 2024-05-28 US disclosed
CN-113039217-B Hybrid supported catalyst and method for preparing polyolefin using the same 株式会社LG化学 2023-05-12 CN disclosed
CN-113166316-B Polyethylene and chlorinated polyethylene thereof 株式会社LG化学 2023-05-02 CN disclosed
US-20220017663-A1 Polyethylene and Its Chlorinated Polyethylene LG CHEM, LTD. (KR) 2022-01-20 US disclosed
US-20220017657-A1 Hybrid Supported Catalyst and Method of Preparing Polyolefin Using the Same LG CHEM, LTD. (KR) 2022-01-20 US disclosed
EP-3865522-A1 POLYETHYLENE, AND CHLORINATED POLYETHYLENE THEREOF LG Chem, Ltd. (KR) 2021-08-18 EP disclosed
EP-3865517-A1 SUPPORTED HYBRID CATALYST AND METHOD FOR PREPARING POLYOLEFIN BY USING SAME LG Chem, Ltd. (KR) 2021-08-18 EP disclosed
CN-113166316-A Polyethylene and chlorinated polyethylene thereof 株式会社LG化学 2021-07-23 CN disclosed
US-6376410-B1 COORDINATION POLYMERIZATION CATALYST ON SUPPORT EXXONMOBIL CHEMICAL PATENTS INC. 2002-04-23 US disclosed
US-6376407-B1 COORDINATION POLYMERIZATION CATALYST EXXONMOBIL CHEMICAL PATENTS INC. 2002-04-23 US disclosed
US-6376627-B1 COORDINATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-04-23 US disclosed
US-6376408-B1 COORDINATION POLYMERIZATION CATALYST ON SUPPORT EXXONMOBIL CHEMICAL PATENTS INC. 2002-04-23 US disclosed
US-6376412-B1 COORDINATION POLYMERIZATION CATALYST ON SUPPORT EXXONMOBIL CHEMICAL PATENTS INC. 2002-04-23 US disclosed
US-6376411-B1 COORDINATION POLYMERIZATION CATALYST ON SUPPORT EXXONMOBIL CHEMICAL PATENTS INC. 2002-04-23 US disclosed
US-6376409-B1 COORDINATION POLYMERIZATION CATALYST ON SUPPORT EXXONMOBIL CHEMICAL PATENTS INC. 2002-04-23 US disclosed
US-6376413-B1 COORDINATION POLYMERIZATION CATALYST ON SUPPORT EXXONMOBIL CHEMICAL PATENTS INC. 2002-04-23 US disclosed
WO-2002002575-A1 METALLOCENES WITH A BRIDGED 4-PHENYL-INDENYL-LIGAND FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2002-01-10 WO disclosed
WO-2001058913-A1 METHOD OF PREPARING GROUP 14 BRIDGED BISCYCLOPENTADIENYL LIGANDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-08-16 WO disclosed