SCHEMBL1808402

SCHEMBL1808402

CC(C)C1=Cc2c(cccc2-c2ccc(C(C)(C)C)cc2)C1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.34
CREBBP Q92793 1/20 0.34
PTAFR P25105 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PLA2G1B P04054 1/20 0.31
NFKB1 P19838 1/20 0.31
CASP3 P42574 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29534991 1.00 BRD4 (0.34) BRD4CREBBPPTAFRAKR1C3AKR1C2
SCHEMBL30338635 0.87 RXRA (0.33) PTAFRNPC1RAB9AALDH1A1PLA2G1B
SCHEMBL6147883 0.87 RXRA (0.33) PTAFRNPC1RAB9AALDH1A1PLA2G1B
SCHEMBL6148287 0.86 RXRA (0.32)
SCHEMBL4467574 0.83 PRCP (0.35)
SCHEMBL31197637 0.83 PRCP (0.35)
SCHEMBL1807786 0.82 BRD4 (0.36) BRD4CREBBPPTAFRNPC1RAB9A
SCHEMBL29594761 0.82 BRD4 (0.36) BRD4CREBBPPTAFRNPC1RAB9A
SCHEMBL26606300 0.81 PNMT (0.31)
Lithium SCHEMBL30438304 0.81 BRD4 (0.36) BRD4CREBBPPTAFRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12460029-B2 Polyolefin LG CHEM, LTD. (KR) 2025-11-04 US disclosed
US-12384860-B2 Hybrid supported metallocene catalyst and process for preparing polyethylene copolymer using the same LG CHEM, LTD. (KR) 2025-08-12 US disclosed
US-12286505-B2 Method for producing metallocene-supported catalyst and metallocene-supported catalyst LG CHEM, LTD. (KR) 2025-04-29 US disclosed
US-12221498-B2 Polyolefin LG CHEM, LTD. (KR) 2025-02-11 US disclosed
US-12098231-B2 Polyolefin LG CHEM, LTD. (KR) 2024-09-24 US disclosed
EP-4032918-B1 POLYOLEFIN LG CHEMICAL LTD (KR) 2024-06-12 EP disclosed
US-11993665-B2 Hybrid supported catalyst and method of preparing polyolefin using the same LG CHEM, LTD. (KR) 2024-05-28 US disclosed
US-11987655-B2 Polyolefin LG CHEM, LTD. (KR) 2024-05-21 US disclosed
CN-114008084-B Method for producing metallocene supported catalyst and metallocene supported catalyst 株式会社LG化学 2024-04-12 CN disclosed
CN-115768804-B Polyolefin 株式会社LG化学 2024-03-29 CN disclosed
WO-2005058916-A2 ORGANOMETALLIC TRANSITION METAL COMPOUND, BISCYCLOPENTADIENYL LIGAND SYSTEM, CATALYST SYSTEM AND PREPARATION OF POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2005-06-30 WO disclosed
EP-1548037-A2 Random propylene-ethylene copolymers Basell Polyolefine GmbH (DE) 2005-06-29 EP disclosed
EP-1548023-A2 Transition metal compound, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins Basell Polyolefine GmbH (DE) 2005-06-29 EP disclosed
EP-1548022-A2 Transition metal compound, ligand system, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins Basell Polyolefine GmbH (DE) 2005-06-29 EP disclosed
CN-1590422-A Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2005-03-09 CN disclosed
CN-1590355-A Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2005-03-09 CN disclosed
US-20030149199-A1 Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins BASELL POLYPROPYLEN GMBH (DE) 2003-08-07 US disclosed
CN-1433435-A Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2003-07-30 CN disclosed
EP-1250365-A2 TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS Basell Polypropylen GmbH (DE) 2002-10-23 EP disclosed
WO-2001048034-A2 TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2001-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149199-A1 Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins PORCN, PGR, PPOX BRD4 1223/4885CREBBP 2360/4885PTAFR 818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.