Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150682 | 0.88 | KCNA5 (0.48) | KCNH2MEN1KCNA5 | |
| SCHEMBL6148397 | 0.87 | KCNH2 (0.53) | KCNH2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL2964372 | 0.84 | KCNH2 (0.63) | KCNH2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL2963414 | 0.80 | KCNH2 (0.56) | KCNH2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL6094254 | 0.80 | POLB (0.54) | KCNH2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL6094259 | 0.80 | POLB (0.54) | KCNH2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL6146890 | 0.80 | CCR3 (0.37) | KCNH2MEN1KMT2AHTR7 | |
| SCHEMBL2964698 | 0.77 | KCNH2 (0.64) | KCNH2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL6151398 | 0.77 | KCNH2 (0.64) | KCNH2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL6097129 | 0.76 | POLB (0.50) | KCNH2POLBL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235831-B1 | NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2005-03-30 | — | — | EP | claimed |