Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.54 |
| ▸ | PPARG | P37231 | 11/20 | 0.54 |
| ▸ | PPARD | Q03181 | 9/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151404 | 0.95 | PPARA (0.52) | PPARAPPARGPPARDMAPK1NPC1 | |
| SCHEMBL6661730 | 0.88 | PPARG (0.57) | PPARAPPARGPPARDMAPK1NPC1 | |
| SCHEMBL6151208 | 0.85 | PPARG (0.56) | PPARAPPARGPPARDMAPK1NPC1 | |
| SCHEMBL5721437 | 0.83 | PPARG (0.54) | PPARAPPARGPPARD | |
| SCHEMBL6150621 | 0.83 | PPARG (0.54) | PPARAPPARGPPARD | |
| SCHEMBL3969061 | 0.82 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL5362731 | 0.82 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL5390569 | 0.81 | PPARA (0.78) | PPARAPPARGPPARD | |
| SCHEMBL5607025 | 0.78 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL5381217 | 0.78 | PPARA (0.72) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |