Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.57 |
| ▸ | PPARA | Q07869 | 12/20 | 0.57 |
| ▸ | PPARD | Q03181 | 8/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151208 | 0.93 | PPARG (0.56) | PPARGPPARAPPARDMAPK1RAB9A | |
| SCHEMBL6150258 | 0.88 | PPARA (0.54) | PPARGPPARAPPARDMAPK1RAB9A | |
| SCHEMBL3963060 | 0.87 | PPARG (0.54) | PPARGPPARAPPARDMAPK1SMN1; SMN2 | |
| SCHEMBL3963064 | 0.87 | PPARG (0.54) | PPARGPPARAPPARDMAPK1SMN1; SMN2 | |
| SCHEMBL6151404 | 0.86 | PPARA (0.52) | PPARGPPARAPPARDMAPK1RAB9A | |
| SCHEMBL6150621 | 0.84 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL5721437 | 0.84 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL6150234 | 0.82 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL14392282 | 0.79 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL5382693 | 0.79 | PPARG (0.79) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |