Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 16/20 | 0.45 |
| ▸ | PPARA | Q07869 | 16/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658842 | 0.90 | PPARA (0.47) | KMT2APPARGPPARAPPARD | |
| SCHEMBL6150634 | 0.87 | PPARA (0.44) | PPARGPPARAPPARDOPRM1OPRD1 | |
| SCHEMBL6150164 | 0.83 | MTNR1A (0.44) | KMT2APPARGPPARAPPARDMEN1 | |
| SCHEMBL6150597 | 0.82 | PPARA (0.47) | KMT2APPARGPPARAMEN1 | |
| SCHEMBL6658216 | 0.81 | PPARA (0.51) | KMT2APPARGPPARAPPARDMEN1 | |
| SCHEMBL6150925 | 0.80 | PPARA (0.47) | PPARGPPARAPPARD | |
| SCHEMBL6660674 | 0.79 | PPARA (0.48) | PPARGPPARAPPARD | |
| SCHEMBL5360529 | 0.79 | KMT2A (0.50) | KMT2APPARGPPARAPPARDOPRM1 | |
| SCHEMBL5361713 | 0.77 | PPARA (0.48) | KMT2APPARGPPARAPPARD | |
| SCHEMBL5361717 | 0.77 | PPARA (0.48) | KMT2APPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |