Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.66 |
| ▸ | PLA2G1B | P04054 | 10/20 | 0.66 |
| ▸ | THRA | P10827 | 2/20 | 0.66 |
| ▸ | THRB | P10828 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16288652 | 0.81 | TRPV1 (0.64) | — | |
| SCHEMBL16289982 | 0.81 | TRPV1 (0.64) | — | |
| SCHEMBL16289718 | 0.81 | TRPV1 (0.64) | — | |
| SCHEMBL16289717 | 0.81 | TRPV1 (0.64) | — | |
| SCHEMBL597782 | 0.81 | TRPV1 (0.64) | — | |
| SCHEMBL16288651 | 0.81 | TRPV1 (0.64) | — | |
| SCHEMBL10658495 | 0.81 | TRPV1 (0.60) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL5847973 | 0.81 | GPR52 (0.56) | — | |
| SCHEMBL5847965 | 0.81 | GPR52 (0.56) | — | |
| 2-Undecylenic Acid SCHEMBL28305828 | 0.81 | PTPN1 (0.64) | CYP1A2TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482896-A4 | AMINOALKYLPHOSPHONATES AND RELATED COMPOUNDS AS EDG RECEPTOR AGONISTS | MERCK & CO INC (US) | 2005-11-23 | — | — | EP | disclosed |
| EP-1482895-A4 | AMINOALKYLPHOSPHONATES AND RELATED COMPOUNDS AS EDG RECEPTOR AGONISTS | MERCK & CO INC (US) | 2005-04-27 | — | — | EP | disclosed |
| EP-1482896-A2 | AMINOALKYLPHOSPHONATES AND RELATED COMPOUNDS AS EDG RECEPTOR AGONISTS | Merck & Co., Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| EP-1482895-A2 | AMINOALKYLPHOSPHONATES AND RELATED COMPOUNDS AS EDG RECEPTOR AGONISTS | Merck & Co., Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003074008-A2 | AMINOALKYLPHOSPHONATES AND RELATED COMPOUNDS AS EDG RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2003-09-12 | — | — | WO | disclosed |
| WO-2003073986-A2 | AMINOALKYLPHOSPHONATES AND RELATED COMPOUNDS AS EDG RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2003-09-12 | — | — | WO | disclosed |