Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.60 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847973 | 0.85 | GPR52 (0.56) | TRPV1HCAR2TBXAS1ALDH1A1MAPT | |
| SCHEMBL5847965 | 0.85 | GPR52 (0.56) | TRPV1HCAR2TBXAS1ALDH1A1MAPT | |
| SCHEMBL6889033 | 0.81 | ESR1 (0.48) | TRPV1IGF1RALOX15ESR1ESR2 | |
| SCHEMBL6150486 | 0.81 | ATG4B (0.66) | PLA2G1BATG4BTHRATHRBCYP1A2 | |
| SCHEMBL11149396 | 0.81 | GPR52 (0.53) | TRPV1TBXAS1 | |
| SCHEMBL1150822 | 0.80 | TRPV1 (0.61) | TRPV1HCAR2TBXAS1ALDH1A1MAPT | |
| SCHEMBL1009881 | 0.80 | TRPV1 (0.61) | TRPV1HCAR2TBXAS1ALDH1A1MAPT | |
| SCHEMBL16288652 | 0.79 | TRPV1 (0.64) | TRPV1TBXAS1ALDH1A1MAPTSLC6A3 | |
| SCHEMBL597782 | 0.79 | TRPV1 (0.64) | TRPV1TBXAS1ALDH1A1MAPTSLC6A3 | |
| SCHEMBL16289717 | 0.79 | TRPV1 (0.64) | TRPV1TBXAS1ALDH1A1MAPTSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743585-A | PEPTIDES, HYPOTENSIVE AGENTS, HYPERALDOSTERONISM | WARNER-LAMBERT COMPANY (US) | 1988-05-10 | — | — | US | disclosed |