Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 6/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | CA12 | O43570 | 2/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | CA4 | P22748 | 2/20 | 0.69 |
| ▸ | CA5A | P35218 | 2/20 | 0.69 |
| ▸ | CA7 | P43166 | 2/20 | 0.69 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.69 |
| ▸ | CA3 | P07451 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CA6 | P23280 | 1/20 | 0.69 |
| ▸ | CA9 | Q16790 | 1/20 | 0.69 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 9/20 | 0.56 |
| ▸ | ALPI | P09923 | 7/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669657 | 0.85 | KDM4E (0.77) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL29363459 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL9283960 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL120173 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL9812694 | 0.80 | KDM4E (0.89) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL9812699 | 0.79 | KDM4E (0.93) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Haloxon SCHEMBL167194 | 0.77 | KDM4E (0.65) | KDM4EALDH1A1HPGDTDP1CA12 | |
| SCHEMBL15842938 | 0.77 | KDM4E (1.00) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL3750396 | 0.76 | KDM4E (0.86) | KDM4EALDH1A1HPGDTDP1CA12 | |
| SCHEMBL3265953 | 0.76 | KDM4E (0.62) | KDM4EALDH1A1HPGDTDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557547-B2 | Phosphotriesterase from agrobacterium radiobacter P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2013-10-15 | — | — | US | disclosed |
| US-20130040367-A1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2013-02-14 | — | — | US | disclosed |
| US-8293244-B2 | for use in pesticide bioremediation strategies; biosensors; genetic engineering; solid phase synthesis | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-10-23 | — | — | US | disclosed |
| EP-1392825-A4 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMW SCIENT IND RES ORG (AU) | 2005-01-26 | — | — | EP | disclosed |
| US-20040161818-A1 | Phosphotriesterase from agrobacterium radiobacter p230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-08-19 | — | — | US | disclosed |
| EP-1392825-A1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002092803-A1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040161818-A1 | Phosphotriesterase from agrobacterium radiobacter p230 | PPA1, PHPT1, DPY30 | KDM4E 841/4885ALDH1A1 1959/4885HPGD 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.