Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.77 |
| ▸ | HPGD | P15428 | 6/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | CA12 | O43570 | 2/20 | 0.77 |
| ▸ | CA1 | P00915 | 2/20 | 0.77 |
| ▸ | CA4 | P22748 | 2/20 | 0.77 |
| ▸ | CA5A | P35218 | 2/20 | 0.77 |
| ▸ | CA7 | P43166 | 2/20 | 0.77 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.77 |
| ▸ | CA3 | P07451 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | CA6 | P23280 | 1/20 | 0.77 |
| ▸ | CA9 | Q16790 | 1/20 | 0.77 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.77 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | ALPL | P05186 | 9/20 | 0.61 |
| ▸ | ALPI | P09923 | 7/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Haloxon SCHEMBL167194 | 0.89 | KDM4E (0.65) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL120173 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL9283960 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL29363459 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HPGDTDP1CA12 | |
| SCHEMBL6150849 | 0.85 | KDM4E (0.69) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL9812694 | 0.84 | KDM4E (0.89) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL9812699 | 0.84 | KDM4E (0.93) | KDM4EALDH1A1HPGDTDP1CA12 | |
| SCHEMBL15842938 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1HPGDTDP1CA12 | |
| Coumaphos SCHEMBL3750396 | 0.80 | KDM4E (0.86) | KDM4EALDH1A1HPGDTDP1CA12 | |
| SCHEMBL3265953 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1HPGDTDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021054927-A2 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2021-03-25 | — | — | WO | claimed |
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2020-02-13 | — | — | US | claimed |
| US-9622969-B2 | Polymer conjugated protein micelles | SOUTH DAKOTA STATE UNIV (US) | 2017-04-18 | — | — | US | claimed |
| CN-104194607-B | The preparation method of fast light and water proofing property waterborne flame retardant polyurethane coating and adhesive | DUAN XIAONING (CN) | 2016-05-11 | — | — | CN | claimed |
| CN-104087149-B | A kind of preparation method of light-resistant waterborne polyurethane coating | DUAN BAORONG (CN) | 2016-04-27 | — | — | CN | claimed |
| US-20140370110-A1 | POLYMER CONJUGATED PROTEIN MICELLES | SOUTH DAKOTA STATE UNIVERSITY (US) | 2014-12-18 | — | — | US | claimed |
| CN-104194607-A | Preparation method of light-resistant and waterproof water-based flame retardant polyurethane coating and adhesive | DUAN XIAONING | 2014-12-10 | — | — | CN | claimed |
| CN-104087149-A | Method for preparing light-fast waterborne polyurethane coating material | DUAN BAORONG | 2014-10-08 | — | — | CN | claimed |
| CN-103819992-A | Preparation method of light resistance coating | DUAN BAORONG | 2014-05-28 | — | — | CN | claimed |
| CN-102703401-A | Phosphotriesterase from agrobacterium radiobacter p230 | COMMW SCIENT IND RES ORG | 2012-10-03 | — | — | CN | claimed |
| WO-2012041965-A1 | PROCESS FOR PRODUCING DIALKYLPHOSPHOTRIESTERS OF NUCLEOSIDES BY ENZYMATIC TRANSESTERIFICATION AND DEPROTECTION THEREOF FOR PRODUCING NUCLEOSIDE MONOPHOSPHATES | UNIVERSIDAD NACIONAL DE QUILMES (AR) | 2012-04-05 | — | — | WO | claimed |
| CN-102229918-A | Phosphotriesterase from agrobacterium radiobacter P230 | COMMW SCIENT IND RES ORG | 2011-11-02 | — | — | CN | claimed |
| EP-1392825-B1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMW SCIENT IND RES ORG (AU) | 2011-01-12 | — | — | EP | claimed |
| US-20070021360-A1 | Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase | EPIGENESIS PHARMACEUTICALS, LLC | 2007-01-25 | — | — | US | claimed |
| EP-1392825-A4 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMW SCIENT IND RES ORG (AU) | 2005-01-26 | — | — | EP | claimed |
| US-20040161818-A1 | Phosphotriesterase from agrobacterium radiobacter p230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-08-19 | — | — | US | claimed |
| CN-1509329-A | Phosphotriesterase from Agrobacterium radiobacter P230 | �����ѧ�����о���֯ | 2004-06-30 | — | — | CN | claimed |
| EP-1392825-A1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-03-03 | — | — | EP | claimed |
| WO-2002092803-A1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2002-11-21 | — | — | WO | claimed |
| CN-85105585-A | PROCESS OF PRODUCING OIL EMULSIONS FOR KILLING SILKWORM FLIES | — | 1987-01-07 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040161818-A1 | Phosphotriesterase from agrobacterium radiobacter p230 | PPA1, PHPT1, DPY30 | KDM4E 841/4885ALDH1A1 1959/4885HPGD 2553/4885 |
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | GSTK1, GSTO1, GSTM2 | KDM4E 4520/4885ALDH1A1 2491/4885HPGD 348/4885 |
| US-20140370110-A1 | POLYMER CONJUGATED PROTEIN MICELLES | MTDH, PSMG3, GHITM | KDM4E 3234/4885ALDH1A1 4150/4885HPGD 2962/4885 |
| US-20070021360-A1 | Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase | RECQL, GSS, DDX17 | KDM4E 4247/4885ALDH1A1 1102/4885HPGD 1833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.