Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664536 | 0.93 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1MAPTKAT2B | |
| SCHEMBL6151420 | 0.89 | ALDH1A1 (0.62) | ALDH1A1TSHRTDP1MAPTKAT2B | |
| SCHEMBL5718533 | 0.83 | MAPT (0.55) | ALDH1A1TDP1MAPTKAT2BPOLB | |
| SCHEMBL7666964 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1MAPTKAT2B | |
| SCHEMBL5718338 | 0.82 | MAPT (0.46) | ALDH1A1MAPTKAT2BPOLBPKM | |
| SCHEMBL6151779 | 0.82 | CYP19A1 (0.50) | ALDH1A1TSHRTDP1MAPTKAT2B | |
| SCHEMBL5718310 | 0.79 | MAPT (0.38) | ALDH1A1MAPTKAT2BPOLBPKM | |
| SCHEMBL5718453 | 0.78 | MAPT (0.44) | ALDH1A1TDP1MAPTKAT2BPOLB | |
| SCHEMBL5718347 | 0.78 | MAPT (0.42) | ALDH1A1TSHRTDP1MAPTKAT2B | |
| SCHEMBL6571775 | 0.77 | POLB (0.42) | ALDH1A1TSHRMAPTKAT2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018508-B1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | OREAL (FR) | 2005-05-04 | — | — | EP | disclosed |
| EP-1018508-A1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | L'OREAL (FR) | 2000-07-12 | — | — | EP | disclosed |