Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | QPCT | Q16769 | 6/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151785 | 0.89 | ALDH1A1 (0.64) | CYP19A1ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL5718326 | 0.83 | QPCT (0.56) | CYP19A1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL9940645 | 0.83 | MAPT (0.54) | CYP19A1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL6150869 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1KDM4ELMNA | |
| SCHEMBL7642996 | 0.80 | QPCT (0.56) | CYP19A1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL5718416 | 0.78 | CYP19A1 (0.50) | CYP19A1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL6151788 | 0.78 | CYP19A1 (0.53) | CYP19A1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL7665095 | 0.77 | CYP19A1 (0.49) | CYP19A1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL5189414 | 0.77 | CYP19A1 (0.60) | CYP19A1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL5718214 | 0.77 | ALDH1A1 (0.49) | CYP19A1ALDH1A1KDM4ELMNAQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018508-B1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | OREAL (FR) | 2005-05-04 | — | — | EP | disclosed |
| US-6464731-B1 | 1-(3-(4-AMINO-2-CHLORO-5-NITROPHENYLAMINO)PROPYL)-3-METHYL-3H -IMIDAZOL-1-IUM BROMIDE USED AS DIRECT HAIR DYES; SOLUBILITY AND PHOTOSTABILITY | L'OREAL S.A. (FR) | 2002-10-15 | — | — | US | disclosed |
| EP-1018508-A1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | L'OREAL (FR) | 2000-07-12 | — | — | EP | disclosed |