Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056165 | 0.86 | MAPT (0.50) | ALDH1A1MAPTTDP1LMNAHTT | |
| SCHEMBL11054749 | 0.85 | ALDH1A1 (0.51) | ALDH1A1GAAGFERMAPTTDP1 | |
| SCHEMBL2367787 | 0.84 | MAPT (0.61) | ALDH1A1GAAGFERMAPTTDP1 | |
| SCHEMBL14877793 | 0.83 | MAPT (0.67) | ALDH1A1GAAGFERMAPTTDP1 | |
| SCHEMBL5956136 | 0.82 | MAPT (0.51) | ALDH1A1GAAMAPTTDP1LMNA | |
| SCHEMBL9498095 | 0.80 | MAPT (0.54) | ALDH1A1GAAGFERMAPTTDP1 | |
| SCHEMBL1819446 | 0.80 | MAPT (0.54) | ALDH1A1MAPTTDP1LMNAHTT | |
| SCHEMBL11876774 | 0.80 | MAPT (0.56) | ALDH1A1GAAGFERMAPTTDP1 | |
| SCHEMBL6151524 | 0.80 | FFAR4 (0.78) | ALDH1A1GAAMAPTTDP1LMNA | |
| SCHEMBL16671925 | 0.78 | APP (0.61) | ALDH1A1GAAGFERMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018508-B1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | OREAL (FR) | 2005-05-04 | — | — | EP | disclosed |
| US-6464731-B1 | 1-(3-(4-AMINO-2-CHLORO-5-NITROPHENYLAMINO)PROPYL)-3-METHYL-3H -IMIDAZOL-1-IUM BROMIDE USED AS DIRECT HAIR DYES; SOLUBILITY AND PHOTOSTABILITY | L'OREAL S.A. (FR) | 2002-10-15 | — | — | US | disclosed |
| EP-1018508-A1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | L'OREAL (FR) | 2000-07-12 | — | — | EP | disclosed |
| US-4637821-A | HAIR, DYEING | L'OREAL (FR) | 1987-01-20 | — | — | US | disclosed |
| US-4511360-A | Dyeing compositions based on oxidation dyestuff precursors and on nitro benzene dyestuffs and their use for dyeing keratin fibres | L'OREAL (FR) | 1985-04-16 | — | — | US | disclosed |
| US-4470826-A | HAIR DYES, NITRO DYES, DIRECT DYES | L'OREAL (FR) | 1984-09-11 | — | — | US | disclosed |