Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14871745 | 0.90 | APP (0.65) | APPALDH1A1GAAGFERFFAR4 | |
| SCHEMBL7595414 | 0.88 | ALDH1A1 (0.70) | ALDH1A1GAAGFERFFAR4LMNA | |
| SCHEMBL7579730 | 0.85 | APP (0.82) | APPALDH1A1GAAGFERFFAR4 | |
| SCHEMBL16671927 | 0.85 | CA1 (0.64) | APPALDH1A1GAAGFERFFAR4 | |
| SCHEMBL2367811 | 0.84 | APP (0.62) | APPALDH1A1GAAGFERFFAR4 | |
| SCHEMBL16671926 | 0.80 | METAP2 (0.60) | APPALDH1A1GAAGFERFFAR4 | |
| SCHEMBL3379842 | 0.79 | FFAR4 (0.60) | APPALDH1A1GAAGFERFFAR4 | |
| SCHEMBL27829690 | 0.79 | FFAR4 (0.65) | APPALDH1A1GAAGFERFFAR4 | |
| SCHEMBL6151145 | 0.78 | ALDH1A1 (0.55) | APPALDH1A1GAAGFERFFAR4 | |
| SCHEMBL398000 | 0.78 | LMNA (0.70) | APPALDH1A1GAALMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018393-B2 | Method for preparing 2-(N-substituted)-amino-benzimidazole derivatives | ABA CHEMICALS CORPORATION (CN) | 2015-04-28 | — | — | US | disclosed |
| US-9018393-B2 | Method for preparing 2-(N-substituted)-amino-benzimidazole derivatives | ABA CHEMICALS CORPORATION (CN) | 2015-04-28 | — | — | US | disclosed |