Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nandrolone Phenpropionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR known ✓ | P10275 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.92 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.64 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.64 |
| ▸ | SHBG | P04278 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nandrolone Phenpropionate SCHEMBL15285479 | 0.96 | MAPT (1.00) | MAPTLMNAALDH1A1SERPINA6SLC22A1 | |
| Nandrolone Phenpropionate SCHEMBL8443 | 0.96 | MAPT (1.00) | MAPTLMNAALDH1A1SERPINA6SLC22A1 | |
| Nandrolone Phenpropionate SCHEMBL29396630 | 0.96 | MAPT (1.00) | MAPTLMNAALDH1A1SERPINA6SLC22A1 | |
| Nandrolone Phenpropionate SCHEMBL29290732 | 0.93 | MAPT (0.93) | MAPTLMNAALDH1A1SERPINA6SLC22A1 | |
| Nandrolone Phenpropionate SCHEMBL1767545 | 0.89 | MAPT (0.86) | MAPTLMNAALDH1A1SERPINA6SLC22A1 | |
| Nandrolone SCHEMBL10963149 | 0.87 | MAPT (0.72) | MAPTLMNAALDH1A1SERPINA6SLC22A1 | |
| Nandrolone Phenpropionate SCHEMBL28167686 | 0.87 | MAPT (0.82) | MAPTLMNAALDH1A1SERPINA6SLC22A1 | |
| SCHEMBL21067996 | 0.86 | MAPT (0.84) | MAPTLMNAALDH1A1SERPINA6SLC22A1 | |
| Nandrolone Phenpropionate SCHEMBL3675534 | 0.85 | MAPT (0.79) | MAPTLMNAALDH1A1SERPINA6SLC22A1 | |
| SCHEMBL23752494 | 0.84 | MAPT (0.78) | MAPTLMNAALDH1A1SERPINA6SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305029-A4 | METHOD OF INCREASING SENSITIVITY OF MAMMOGRAPHY | CLEVELAND CLINIC FOUNDATION (US) | 2005-05-04 | — | — | EP | disclosed |
| EP-1305029-A1 | METHOD OF INCREASING SENSITIVITY OF MAMMOGRAPHY | THE CLEVELAND CLINIC FOUNDATION (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002009721-A1 | METHOD OF INCREASING SENSITIVITY OF MAMMOGRAPHY | THE CLEVELAND CLINIC FOUNDATION (US) | 2002-02-07 | — | — | WO | disclosed |
| EP-0929295-A4 | — | — | 1999-08-18 | — | — | EP | disclosed |
| EP-0929295-A1 | COMBINED PHARMACEUTICAL ESTROGEN-ANDROGEN-PROGESTIN ORAL CONTRACEPTIVE | WAKE FOREST UNIVERSITY (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998001115-A1 | COMBINED PHARMACEUTICAL ESTROGEN-ANDROGEN-PROGESTIN ORAL CONTRACEPTIVE | WAKE FOREST UNIVERSITY (US) | 1998-01-15 | — | — | WO | disclosed |