Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077102 | 0.95 | HIF1A (0.48) | HIF1AALDH1A1S1PR1PRKXACVR1 | |
| SCHEMBL6151249 | 0.90 | HIF1A (0.44) | HIF1AALDH1A1S1PR1PRKXACVR1 | |
| SCHEMBL6151245 | 0.90 | HIF1A (0.44) | HIF1AALDH1A1S1PR1PRKXACVR1 | |
| SCHEMBL5075977 | 0.90 | RAB9A (0.48) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5079483 | 0.88 | MRGPRX4 (0.46) | HIF1AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL5075922 | 0.88 | FABP3 (0.52) | ALDH1A1S1PR1S1PR5MEN1KMT2A | |
| SCHEMBL5080507 | 0.88 | TP53 (0.41) | HIF1AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL5074492 | 0.87 | TP53 (0.40) | HIF1AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL5076979 | 0.87 | TP53 (0.40) | HIF1AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL5080373 | 0.87 | HTT (0.40) | HIF1AALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494991-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | Isagro Ricerca S.r.l. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087032-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | ISAGRO RICERCA S.R.L. (IT) | 2003-10-23 | — | — | WO | disclosed |